BRD-K71799778_BML-259_SW948_6.0_h_80.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K71799778_BML-259_SW948_6.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ANGPTL2 angiopoietin-like 2
ASCL1 achaete-scute family bHLH transcription factor 1
ATF3 activating transcription factor 3
BTG3 BTG family, member 3
CD9 CD9 molecule
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COL3A1 collagen, type III, alpha 1
CORO1A coronin, actin binding protein, 1A
CPE carboxypeptidase E
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DSP desmoplakin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
GPM6B glycoprotein M6B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTRA1 HtrA serine peptidase 1
IER5 immediate early response 5
MECOM MDS1 and EVI1 complex locus
MT1F metallothionein 1F
MUC16 mucin 16, cell surface associated
PPAP2B phosphatidic acid phosphatase type 2B
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
SULF1 sulfatase 1
WLS wntless Wnt ligand secretion mediator
ZMIZ1 zinc finger, MIZ-type containing 1

decreased expression

Symbol Name
AHNAK AHNAK nucleoprotein
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
AURKA aurora kinase A
BIK BCL2-interacting killer (apoptosis-inducing)
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CST3 cystatin C
CTSH cathepsin H
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL5 chemokine (C-X-C motif) ligand 5
DCK deoxycytidine kinase
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
FZD7 frizzled class receptor 7
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GRB14 growth factor receptor-bound protein 14
GTPBP8 GTP-binding protein 8 (putative)
H1F0 H1 histone family, member 0
HOXB7 homeobox B7
HOXC6 homeobox C6
KIAA1033 KIAA1033
KIF20A kinesin family member 20A
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LRP10 low density lipoprotein receptor-related protein 10
MAP7 microtubule-associated protein 7
MYO6 myosin VI
NEFL neurofilament, light polypeptide
NNMT nicotinamide N-methyltransferase
NOSIP nitric oxide synthase interacting protein
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRN1 neuritin 1
PARP2 poly (ADP-ribose) polymerase 2
PIP prolactin-induced protein
PLK1 polo-like kinase 1
PTTG1 pituitary tumor-transforming 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPL36 ribosomal protein L36
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SCGB2A2 secretoglobin, family 2A, member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC25A46 solute carrier family 25, member 46
SRSF6 serine/arginine-rich splicing factor 6
SYPL1 synaptophysin-like 1
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TLE4 transducin-like enhancer of split 4
TNC tenascin C
TOP2A topoisomerase (DNA) II alpha 170kDa
TOX3 TOX high mobility group box family member 3
TRAF5 TNF receptor-associated factor 5
TRIM14 tripartite motif containing 14
UBE2S ubiquitin-conjugating enzyme E2S
UGCG UDP-glucose ceramide glucosyltransferase
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZW10 zw10 kinetochore protein