BRD-K71489689_2-(4-(tert-butyl)benzamido)-4,5-dichlorobenzoic acid KUC107686N_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K71489689_2-(4-(tert-butyl)benzamido)-4,5-dichlorobenzoic acid KUC107686N_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
CARS cysteinyl-tRNA synthetase
CBS cystathionine-beta-synthase
CCL4 chemokine (C-C motif) ligand 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRABP2 cellular retinoic acid binding protein 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
G0S2 G0/G1 switch 2
GADD45B growth arrest and DNA-damage-inducible, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
KRT5 keratin 5, type II
MARS methionyl-tRNA synthetase
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
SARS seryl-tRNA synthetase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
STC2 stanniocalcin 2
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
FOLR1 folate receptor 1 (adult)
HIST1H2BK histone cluster 1, H2bk
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXC6 homeobox C6
KIAA0101 KIAA0101
LTF lactotransferrin
NR2F2 nuclear receptor subfamily 2, group F, member 2
PCNA proliferating cell nuclear antigen
RBPMS RNA binding protein with multiple splicing
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
TYMS thymidylate synthetase
VCAM1 vascular cell adhesion molecule 1