BRD-K71133585_Sulfaquinoxaline sodium salt_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K71133585_Sulfaquinoxaline sodium salt_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACTN1 actinin, alpha 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BEX1 brain expressed, X-linked 1
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
CDC25B cell division cycle 25B
CHI3L2 chitinase 3-like 2
CLINT1 clathrin interactor 1
CLU clusterin
CPVL carboxypeptidase, vitellogenic-like
CXCL8 chemokine (C-X-C motif) ligand 8
FABP7 fatty acid binding protein 7, brain
FCGBP Fc fragment of IgG binding protein
FGFR3 fibroblast growth factor receptor 3
GATA6 GATA binding protein 6
GSTA1 glutathione S-transferase alpha 1
GTPBP8 GTP-binding protein 8 (putative)
IFI6 interferon, alpha-inducible protein 6
JMJD6 jumonji domain containing 6
LCN2 lipocalin 2
LTF lactotransferrin
METTL7A methyltransferase like 7A
NR2F6 nuclear receptor subfamily 2, group F, member 6
OAT ornithine aminotransferase
PLAC8 placenta-specific 8
PRDX2 peroxiredoxin 2
PROM1 prominin 1
RBP1 retinol binding protein 1, cellular
RNASE6 ribonuclease, RNase A family, k6
SFRP1 secreted frizzled-related protein 1
STXBP1 syntaxin binding protein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM4SF4 transmembrane 4 L six family member 4
TNIP1 TNFAIP3 interacting protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AIM1 absent in melanoma 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARL4C ADP-ribosylation factor-like 4C
CAV1 caveolin 1, caveolae protein, 22kDa
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CD52 CD52 molecule
COL11A1 collagen, type XI, alpha 1
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CPA3 carboxypeptidase A3 (mast cell)
CRIP2 cysteine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CXCL13 chemokine (C-X-C motif) ligand 13
DCN decorin
DUSP2 dual specificity phosphatase 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FBN2 fibrillin 2
FN1 fibronectin 1
GHR growth hormone receptor
GUSBP3 glucuronidase, beta pseudogene 3
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HEATR1 HEAT repeat containing 1
ICAM1 intercellular adhesion molecule 1
IGKV4-1 immunoglobulin kappa variable 4-1
IL7R interleukin 7 receptor
JCHAIN joining chain of multimeric IgA and IgM
KDM5D lysine (K)-specific demethylase 5D
KRT17 keratin 17, type I
LUM lumican
MME membrane metallo-endopeptidase
MTSS1 metastasis suppressor 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NNT nicotinamide nucleotide transhydrogenase
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPTX2 neuronal pentraxin II
NVL nuclear VCP-like
PAX8 paired box 8
PEG10 paternally expressed 10
PROS1 protein S (alpha)
PRSS21 protease, serine, 21 (testisin)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SULF1 sulfatase 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIMP3 TIMP metallopeptidase inhibitor 3
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
VCAM1 vascular cell adhesion molecule 1