BRD-K70792160_Akt inhibitor X_MCF7_6.0_h_24.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K70792160_Akt inhibitor X_MCF7_6.0_h_24.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD10 ankyrin repeat domain 10
CCNG2 cyclin G2
CCR7 chemokine (C-C motif) receptor 7
CDK19 cyclin-dependent kinase 19
CST3 cystatin C
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
DUSP4 dual specificity phosphatase 4
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GEM GTP binding protein overexpressed in skeletal muscle
GRN granulin
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IGHM immunoglobulin heavy constant mu
INSIG1 insulin induced gene 1
KLHL24 kelch-like family member 24
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CFH complement factor H
COL5A2 collagen, type V, alpha 2
HN1 hematological and neurological expressed 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
PRPF4 pre-mRNA processing factor 4
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9