BRD-K70281171_U 99194 maleate_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K70281171_U 99194 maleate_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DUSP6 dual specificity phosphatase 6
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HIST1H2BG histone cluster 1, H2bg
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IL7R interleukin 7 receptor
LCN2 lipocalin 2
LGALS1 lectin, galactoside-binding, soluble, 1
MEIS2 Meis homeobox 2
NDRG2 NDRG family member 2
PROM1 prominin 1
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP1 secreted frizzled-related protein 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
CLIC5 chloride intracellular channel 5
CRABP1 cellular retinoic acid binding protein 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DICER1 dicer 1, ribonuclease type III
EAPP E2F-associated phosphoprotein
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GCH1 GTP cyclohydrolase 1
HACD2 3-hydroxyacyl-CoA dehydratase 2
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HPRT1 hypoxanthine phosphoribosyltransferase 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LOXL1 lysyl oxidase-like 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NRN1 neuritin 1
PDGFA platelet-derived growth factor alpha polypeptide
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RPS11 ribosomal protein S11
SEPP1 selenoprotein P, plasma, 1
SFN stratifin
SYBU syntabulin (syntaxin-interacting)
TMEM176B transmembrane protein 176B
TNS3 tensin 3
TYRP1 tyrosinase-related protein 1
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
WSB2 WD repeat and SOCS box containing 2
ZMYM2 zinc finger, MYM-type 2