BRD-K69932463_AZD-8055_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

184 genes differentially expressed following the BRD-K69932463_AZD-8055_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACD adrenocortical dysplasia homolog (mouse)
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA4 annexin A4
ARG1 arginase 1
C19ORF54 chromosome 19 open reading frame 54
C6ORF48 chromosome 6 open reading frame 48
CALML5 calmodulin-like 5
CAMLG calcium modulating ligand
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CD44 CD44 molecule (Indian blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CIRBP cold inducible RNA binding protein
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTSK cathepsin K
DALRD3 DALR anticodon binding domain containing 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF4B eukaryotic translation initiation factor 4B
ETHE1 ethylmalonic encephalopathy 1
FAR2 fatty acyl CoA reductase 2
FOXD1 forkhead box D1
FOXG1 forkhead box G1
FOXN3 forkhead box N3
FXR1 fragile X mental retardation, autosomal homolog 1
GALC galactosylceramidase
GLTSCR2 glioma tumor suppressor candidate region gene 2
GPX4 glutathione peroxidase 4
GSDMB gasdermin B
H1F0 H1 histone family, member 0
HAUS4 HAUS augmin-like complex, subunit 4
HEBP1 heme binding protein 1
HOXB7 homeobox B7
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IGBP1 immunoglobulin (CD79A) binding protein 1
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
INSR insulin receptor
IPO7 importin 7
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
KLF2 Kruppel-like factor 2
KRT17 keratin 17, type I
LETMD1 LETM1 domain containing 1
LOC399491
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NARFL nuclear prelamin A recognition factor-like
NONO non-POU domain containing, octamer-binding
PARP6 poly (ADP-ribose) polymerase family, member 6
PGLS 6-phosphogluconolactonase
PHYH phytanoyl-CoA 2-hydroxylase
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1
POSTN periostin, osteoblast specific factor
PTPRO protein tyrosine phosphatase, receptor type, O
PXMP2 peroxisomal membrane protein 2, 22kDa
RPL36 ribosomal protein L36
S100A7 S100 calcium binding protein A7
SET SET nuclear proto-oncogene
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SOX4 SRY (sex determining region Y)-box 4
SQSTM1 sequestosome 1
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
SULF1 sulfatase 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TBX2 T-box 2
TCEA2 transcription elongation factor A (SII), 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TM4SF4 transmembrane 4 L six family member 4
TPP1 tripeptidyl peptidase I
TRAF3IP2 TRAF3 interacting protein 2
VAT1 vesicle amine transport 1
WDR13 WD repeat domain 13
ZNF277 zinc finger protein 277
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACAT2 acetyl-CoA acetyltransferase 2
ADGRG1 adhesion G protein-coupled receptor G1
ADI1 acireductone dioxygenase 1
ALDOC aldolase C, fructose-bisphosphate
ARF4 ADP-ribosylation factor 4
ARG2 arginase 2
ARHGAP29 Rho GTPase activating protein 29
ASNS asparagine synthetase (glutamine-hydrolyzing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C1ORF116 chromosome 1 open reading frame 116
C8ORF4 chromosome 8 open reading frame 4
CALU calumenin
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCND3 cyclin D3
CD59 CD59 molecule, complement regulatory protein
CFB complement factor B
CFH complement factor H
CLU clusterin
CTSC cathepsin C
CYB5A cytochrome b5 type A (microsomal)
CYCS cytochrome c, somatic
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EGF epidermal growth factor
ENO1 enolase 1, (alpha)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPRS glutamyl-prolyl-tRNA synthetase
FADS2 fatty acid desaturase 2
FAM162A family with sequence similarity 162, member A
FAM98A family with sequence similarity 98, member A
FKBP14 FK506 binding protein 14, 22 kDa
FOLR1 folate receptor 1 (adult)
GLIPR1 GLI pathogenesis-related 1
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GSTM3 glutathione S-transferase mu 3 (brain)
H2BFS H2B histone family, member S (pseudogene)
HAT1 histone acetyltransferase 1
HIST1H2BK histone cluster 1, H2bk
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HYOU1 hypoxia up-regulated 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP4 insulin-like growth factor binding protein 4
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
INSIG1 insulin induced gene 1
JCHAIN joining chain of multimeric IgA and IgM
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
L1CAM L1 cell adhesion molecule
LDLR low density lipoprotein receptor
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRC59 leucine rich repeat containing 59
MAL mal, T-cell differentiation protein
MALL mal, T-cell differentiation protein-like
MARS methionyl-tRNA synthetase
MB myoglobin
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
MSMO1 methylsterol monooxygenase 1
MYCBP MYC binding protein
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NME1 NME/NM23 nucleoside diphosphate kinase 1
ODC1 ornithine decarboxylase 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDIA6 protein disulfide isomerase family A, member 6
PEG10 paternally expressed 10
PELI1 pellino E3 ubiquitin protein ligase 1
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PHGDH phosphoglycerate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PITX1 paired-like homeodomain 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PON2 paraoxonase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSAT1 phosphoserine aminotransferase 1
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSPH phosphoserine phosphatase
PYCR1 pyrroline-5-carboxylate reductase 1
QPRT quinolinate phosphoribosyltransferase
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SELENBP1 selenium binding protein 1
SGCE sarcoglycan, epsilon
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SQLE squalene epoxidase
SRPRB signal recognition particle receptor, B subunit
SSR1 signal sequence receptor, alpha
TFB2M transcription factor B2, mitochondrial
TFRC transferrin receptor
TIGAR TP53 induced glycolysis regulatory phosphatase
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TNC tenascin C
TPD52 tumor protein D52
TSPAN13 tetraspanin 13
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
USP6NL USP6 N-terminal like
VAMP8 vesicle-associated membrane protein 8