| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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200 genes differentially expressed following the BRD-K69840642_HDAC6 inhibitor ISOX_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AAK1 | AP2 associated kinase 1 |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ABAT | 4-aminobutyrate aminotransferase |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ASS1 | argininosuccinate synthase 1 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCNG2 | cyclin G2 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDK7 | cyclin-dependent kinase 7 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CLDN3 | claudin 3 |
| CLDND1 | claudin domain containing 1 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DSP | desmoplakin |
| DUSP14 | dual specificity phosphatase 14 |
| EFNB2 | ephrin-B2 |
| ENAH | enabled homolog (Drosophila) |
| FAM117A | family with sequence similarity 117, member A |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FKBP1A | FK506 binding protein 1A, 12kDa |
| FOXO4 | forkhead box O4 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GM2A | GM2 ganglioside activator |
| GSN | gelsolin |
| HECA | headcase homolog (Drosophila) |
| HK1 | hexokinase 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| ICAM1 | intercellular adhesion molecule 1 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGLV2-23 | immunoglobulin lambda variable 2-23 |
| INSIG1 | insulin induced gene 1 |
| ITM2A | integral membrane protein 2A |
| JARID2 | jumonji, AT rich interactive domain 2 |
| KAZN | kazrin, periplakin interacting protein |
| KIAA0226L | KIAA0226-like |
| LIMA1 | LIM domain and actin binding 1 |
| LPIN1 | lipin 1 |
| LTA4H | leukotriene A4 hydrolase |
| MAMLD1 | mastermind-like domain containing 1 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MLEC | malectin |
| MLXIP | MLX interacting protein |
| MSMO1 | methylsterol monooxygenase 1 |
| MT1X | metallothionein 1X |
| MXRA7 | matrix-remodelling associated 7 |
| NDRG1 | N-myc downstream regulated 1 |
| NOSIP | nitric oxide synthase interacting protein |
| NPC1 | Niemann-Pick disease, type C1 |
| OPTN | optineurin |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PEG10 | paternally expressed 10 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 |
| PLA2G15 | phospholipase A2, group XV |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PRKCD | protein kinase C, delta |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| RAB31 | RAB31, member RAS oncogene family |
| RAD9A | RAD9 homolog A (S. pombe) |
| RHCG | Rh family, C glycoprotein |
| RND1 | Rho family GTPase 1 |
| S100A14 | S100 calcium binding protein A14 |
| S100A9 | S100 calcium binding protein A9 |
| SCPEP1 | serine carboxypeptidase 1 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SNN | stannin |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| SSBP2 | single-stranded DNA binding protein 2 |
| STK17A | serine/threonine kinase 17a |
| TBPL1 | TBP-like 1 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TKT | transketolase |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TSPAN13 | tetraspanin 13 |
| TSPAN7 | tetraspanin 7 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| XYLT1 | xylosyltransferase I |
| ZSWIM8 | zinc finger, SWIM-type containing 8 |
| Symbol | Name |
|---|---|
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
| ADNP | activity-dependent neuroprotector homeobox |
| AKAP8 | A kinase (PRKA) anchor protein 8 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
| AREG | amphiregulin |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ATF1 | activating transcription factor 1 |
| ATF5 | activating transcription factor 5 |
| BICC1 | BicC family RNA binding protein 1 |
| C1R | complement component 1, r subcomponent |
| C1S | complement component 1, s subcomponent |
| CADM1 | cell adhesion molecule 1 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNA2 | cyclin A2 |
| CCND1 | cyclin D1 |
| CD58 | CD58 molecule |
| CFH | complement factor H |
| COL5A2 | collagen, type V, alpha 2 |
| CREBBP | CREB binding protein |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DUSP3 | dual specificity phosphatase 3 |
| DUSP4 | dual specificity phosphatase 4 |
| EBAG9 | estrogen receptor binding site associated, antigen, 9 |
| EGFR | epidermal growth factor receptor |
| EIF5 | eukaryotic translation initiation factor 5 |
| FAM60A | family with sequence similarity 60, member A |
| FHL2 | four and a half LIM domains 2 |
| FOSL1 | FOS-like antigen 1 |
| FOXM1 | forkhead box M1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPX2 | glutathione peroxidase 2 |
| GSAP | gamma-secretase activating protein |
| GSPT2 | G1 to S phase transition 2 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HOXA5 | homeobox A5 |
| HOXB2 | homeobox B2 |
| HOXB6 | homeobox B6 |
| HOXB7 | homeobox B7 |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL1R1 | interleukin 1 receptor, type I |
| JADE2 | jade family PHD finger 2 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KYNU | kynureninase |
| LAMB1 | laminin, beta 1 |
| LCMT2 | leucine carboxyl methyltransferase 2 |
| LMNB1 | lamin B1 |
| LRRC17 | leucine rich repeat containing 17 |
| LRRC41 | leucine rich repeat containing 41 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MECOM | MDS1 and EVI1 complex locus |
| MRPS18B | mitochondrial ribosomal protein S18B |
| MSLN | mesothelin |
| MZT2A | mitotic spindle organizing protein 2A |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NMI | N-myc (and STAT) interactor |
| NPY1R | neuropeptide Y receptor Y1 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor |
| OBSL1 | obscurin-like 1 |
| PDGFD | platelet derived growth factor D |
| PER2 | period circadian clock 2 |
| PGLS | 6-phosphogluconolactonase |
| PLK1 | polo-like kinase 1 |
| POGK | pogo transposable element with KRAB domain |
| PON2 | paraoxonase 2 |
| PTX3 | pentraxin 3, long |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RELN | reelin |
| RGS1 | regulator of G-protein signaling 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| ST7 | suppression of tumorigenicity 7 |
| STEAP3 | STEAP family member 3, metalloreductase |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TBL1X | transducin (beta)-like 1X-linked |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFDP1 | transcription factor Dp-1 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| THBS1 | thrombospondin 1 |
| TLK1 | tousled-like kinase 1 |
| TMEM5 | transmembrane protein 5 |
| TNS3 | tensin 3 |
| TSPAN8 | tetraspanin 8 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 |
| TXLNA | taxilin alpha |
| TYMS | thymidylate synthetase |
| UBQLN2 | ubiquilin 2 |
| USP1 | ubiquitin specific peptidase 1 |
| USP22 | ubiquitin specific peptidase 22 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
