| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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184 genes differentially expressed following the BRD-K69840642_HDAC6 inhibitor ISOX_DV90_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| ABHD3 | abhydrolase domain containing 3 |
| ACOT7 | acyl-CoA thioesterase 7 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDOC | aldolase C, fructose-bisphosphate |
| AOX1 | aldehyde oxidase 1 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| CA2 | carbonic anhydrase II |
| CALCOCO2 | calcium binding and coiled-coil domain 2 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCDC69 | coiled-coil domain containing 69 |
| CCND3 | cyclin D3 |
| CCNG2 | cyclin G2 |
| CFD | complement factor D (adipsin) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLIC4 | chloride intracellular channel 4 |
| CYB5R1 | cytochrome b5 reductase 1 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DPYSL2 | dihydropyrimidinase-like 2 |
| DUSP1 | dual specificity phosphatase 1 |
| EAF2 | ELL associated factor 2 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FADS1 | fatty acid desaturase 1 |
| FAM117A | family with sequence similarity 117, member A |
| FGL2 | fibrinogen-like 2 |
| FHL1 | four and a half LIM domains 1 |
| FN1 | fibronectin 1 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATA3 | GATA binding protein 3 |
| GLRX | glutaredoxin (thioltransferase) |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HECA | headcase homolog (Drosophila) |
| HES1 | hes family bHLH transcription factor 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNGR1 | interferon gamma receptor 1 |
| IFT57 | intraflagellar transport 57 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INSIG1 | insulin induced gene 1 |
| ITM2A | integral membrane protein 2A |
| KDM5B | lysine (K)-specific demethylase 5B |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LPIN1 | lipin 1 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| MAP7 | microtubule-associated protein 7 |
| MICB | MHC class I polypeptide-related sequence B |
| MMP1 | matrix metallopeptidase 1 |
| NOSIP | nitric oxide synthase interacting protein |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| OAT | ornithine aminotransferase |
| PCDH9 | protocadherin 9 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PEG10 | paternally expressed 10 |
| PEG3 | paternally expressed 3 |
| PLA2G15 | phospholipase A2, group XV |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRSS3 | protease, serine, 3 |
| PTK2B | protein tyrosine kinase 2 beta |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAD9A | RAD9 homolog A (S. pombe) |
| RGS2 | regulator of G-protein signaling 2 |
| RHOB | ras homolog family member B |
| RRAGC | Ras-related GTP binding C |
| SCPEP1 | serine carboxypeptidase 1 |
| SEPT6 | septin 6 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SGCE | sarcoglycan, epsilon |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC38A1 | solute carrier family 38, member 1 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SRGN | serglycin |
| STOM | stomatin |
| SYNGR3 | synaptogyrin 3 |
| TBPL1 | TBP-like 1 |
| TCF21 | transcription factor 21 |
| TCF4 | transcription factor 4 |
| TKTL1 | transketolase-like 1 |
| TOB1 | transducer of ERBB2, 1 |
| TUBA1A | tubulin, alpha 1a |
| TUBB2A | tubulin, beta 2A class IIa |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VIM | vimentin |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADORA2B | adenosine A2b receptor |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ASS1 | argininosuccinate synthase 1 |
| ATF1 | activating transcription factor 1 |
| ATF5 | activating transcription factor 5 |
| CCND1 | cyclin D1 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFI | complement factor I |
| COL3A1 | collagen, type III, alpha 1 |
| COMT | catechol-O-methyltransferase |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
| DCN | decorin |
| DENND2D | DENN/MADD domain containing 2D |
| DKC1 | dyskeratosis congenita 1, dyskerin |
| EFS | embryonal Fyn-associated substrate |
| F12 | coagulation factor XII (Hageman factor) |
| FAM57A | family with sequence similarity 57, member A |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GPM6B | glycoprotein M6B |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| JADE2 | jade family PHD finger 2 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLK10 | kallikrein-related peptidase 10 |
| KRT14 | keratin 14, type I |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) |
| LPL | lipoprotein lipase |
| LTF | lactotransferrin |
| LUM | lumican |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MCM5 | minichromosome maintenance complex component 5 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 |
| MDK | midkine (neurite growth-promoting factor 2) |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MMP7 | matrix metallopeptidase 7 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NRN1 | neuritin 1 |
| NUP62 | nucleoporin 62kDa |
| OBSL1 | obscurin-like 1 |
| PDGFC | platelet derived growth factor C |
| PGLS | 6-phosphogluconolactonase |
| PLK1 | polo-like kinase 1 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRR7 | proline rich 7 (synaptic) |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PTGES | prostaglandin E synthase |
| PTX3 | pentraxin 3, long |
| PUF60 | poly-U binding splicing factor 60KDa |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| S100A2 | S100 calcium binding protein A2 |
| S100A7 | S100 calcium binding protein A7 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC35F2 | solute carrier family 35, member F2 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMAGP | small cell adhesion glycoprotein |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| STEAP3 | STEAP family member 3, metalloreductase |
| STK10 | serine/threonine kinase 10 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TRIM29 | tripartite motif containing 29 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
| WEE1 | WEE1 G2 checkpoint kinase |
| ZFP64 | ZFP64 zinc finger protein |
| ZIC1 | Zic family member 1 |
