BRD-K69516039_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K69516039_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ARMCX3 armadillo repeat containing, X-linked 3
ASNS asparagine synthetase (glutamine-hydrolyzing)
BASP1 brain abundant, membrane attached signal protein 1
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BET1 Bet1 golgi vesicular membrane trafficking protein
BTG1 B-cell translocation gene 1, anti-proliferative
CCNG2 cyclin G2
CCR7 chemokine (C-C motif) receptor 7
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
COL11A1 collagen, type XI, alpha 1
COLEC12 collectin sub-family member 12
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FBN2 fibrillin 2
FKBP11 FK506 binding protein 11, 19 kDa
FKBP14 FK506 binding protein 14, 22 kDa
GAA glucosidase, alpha; acid
GUSBP3 glucuronidase, beta pseudogene 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP4 insulin-like growth factor binding protein 4
KIAA0355 KIAA0355
LTBP3 latent transforming growth factor beta binding protein 3
MKNK2 MAP kinase interacting serine/threonine kinase 2
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MYBPC1 myosin binding protein C, slow type
NUCB2 nucleobindin 2
OXTR oxytocin receptor
PDIA4 protein disulfide isomerase family A, member 4
PDLIM5 PDZ and LIM domain 5
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRAME preferentially expressed antigen in melanoma
PTX3 pentraxin 3, long
QKI QKI, KH domain containing, RNA binding
RAD9A RAD9 homolog A (S. pombe)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A10 S100 calcium binding protein A10
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLN sarcolipin
SPINK1 serine peptidase inhibitor, Kazal type 1
SRRM2 serine/arginine repetitive matrix 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TENM1 teneurin transmembrane protein 1
TSPAN7 tetraspanin 7
TTN titin
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
ANKRD10 ankyrin repeat domain 10
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
BMP2 bone morphogenetic protein 2
BTBD3 BTB (POZ) domain containing 3
CA2 carbonic anhydrase II
CD24 CD24 molecule
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNM1L dynamin 1-like
EIF5A eukaryotic translation initiation factor 5A
EPCAM epithelial cell adhesion molecule
FXYD6 FXYD domain containing ion transport regulator 6
GRIA2 glutamate receptor, ionotropic, AMPA 2
ITGB1BP1 integrin beta 1 binding protein 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAP7 microtubule-associated protein 7
PCDH9 protocadherin 9
PCSK1 proprotein convertase subtilisin/kexin type 1
PERP PERP, TP53 apoptosis effector
PRR7 proline rich 7 (synaptic)
PXMP2 peroxisomal membrane protein 2, 22kDa
RBP4 retinol binding protein 4, plasma
RNF167 ring finger protein 167
RTN1 reticulon 1
SEPP1 selenoprotein P, plasma, 1
SFTPC surfactant protein C
SST somatostatin
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TPD52 tumor protein D52
WISP2 WNT1 inducible signaling pathway protein 2