BRD-K69328504_L-690,488_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K69328504_L-690,488_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA1 actin, alpha 1, skeletal muscle
ADM adrenomedullin
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA2 carbonic anhydrase II
CCND2 cyclin D2
CCR2 chemokine (C-C motif) receptor 2
CD164 CD164 molecule, sialomucin
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CKM creatine kinase, muscle
CLIC5 chloride intracellular channel 5
CNN3 calponin 3, acidic
COL4A5 collagen, type IV, alpha 5
CRYAB crystallin, alpha B
DAPK1 death-associated protein kinase 1
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
FGF13 fibroblast growth factor 13
GATA3 GATA binding protein 3
GLRX glutaredoxin (thioltransferase)
GSTA1 glutathione S-transferase alpha 1
HACD1 3-hydroxyacyl-CoA dehydratase 1
HBE1 hemoglobin, epsilon 1
HILPDA hypoxia inducible lipid droplet-associated
KLHL41 kelch-like family member 41
LAMP5 lysosomal-associated membrane protein family, member 5
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MYOT myotilin
NEB nebulin
NXN nucleoredoxin
OPN3 opsin 3
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PLAGL1 pleiomorphic adenoma gene-like 1
PRKCB protein kinase C, beta
RRAD Ras-related associated with diabetes
RRAGD Ras-related GTP binding D
S100P S100 calcium binding protein P
SFRP1 secreted frizzled-related protein 1
SVIL supervillin
TGFBR3 transforming growth factor, beta receptor III
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNI2 troponin I type 2 (skeletal, fast)
TRAF3IP3 TRAF3 interacting protein 3
TSPAN13 tetraspanin 13
TTN titin
VCAN versican

decreased expression

Symbol Name
BIK BCL2-interacting killer (apoptosis-inducing)
CCL4 chemokine (C-C motif) ligand 4
CCND1 cyclin D1
CCNF cyclin F
CD9 CD9 molecule
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSRP1 cysteine and glycine-rich protein 1
EREG epiregulin
ESR1 estrogen receptor 1
FERMT1 fermitin family member 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
HNMT histamine N-methyltransferase
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
KYNU kynureninase
MARCKSL1 MARCKS-like 1
MT1X metallothionein 1X
NAV2 neuron navigator 2
PLK1 polo-like kinase 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SFPQ splicing factor proline/glutamine-rich
SYT1 synaptotagmin I
TM9SF3 transmembrane 9 superfamily member 3
TXNDC9 thioredoxin domain containing 9