BRD-K68873215_Phosphodiesterase V Inhibitor II_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K68873215_Phosphodiesterase V Inhibitor II_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDOB aldolase B, fructose-bisphosphate
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CCDC85B coiled-coil domain containing 85B
COLEC12 collectin sub-family member 12
DSP desmoplakin
ECM1 extracellular matrix protein 1
EFHD1 EF-hand domain family, member D1
EMP1 epithelial membrane protein 1
EREG epiregulin
GREM1 gremlin 1, DAN family BMP antagonist
MAOB monoamine oxidase B
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SPARCL1 SPARC-like 1 (hevin)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THBS2 thrombospondin 2

decreased expression

Symbol Name
AMD1 adenosylmethionine decarboxylase 1
ATMIN ATM interactor
BAG3 BCL2-associated athanogene 3
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CRK v-crk avian sarcoma virus CT10 oncogene homolog
FAM46A family with sequence similarity 46, member A
FOLR1 folate receptor 1 (adult)
HIST1H2BK histone cluster 1, H2bk
MAP2K5 mitogen-activated protein kinase kinase 5
MARCKS myristoylated alanine-rich protein kinase C substrate
RPS11 ribosomal protein S11
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SUB1 SUB1 homolog (S. cerevisiae)
UBE2S ubiquitin-conjugating enzyme E2S
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon