BRD-K68407802_KIN001-055_HA1E_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K68407802_KIN001-055_HA1E_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APLP2 amyloid beta (A4) precursor-like protein 2
APOD apolipoprotein D
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BEX1 brain expressed, X-linked 1
CPM carboxypeptidase M
CTSH cathepsin H
EFS embryonal Fyn-associated substrate
FAM63A family with sequence similarity 63, member A
FHL1 four and a half LIM domains 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
HOXC10 homeobox C10
IGFBP4 insulin-like growth factor binding protein 4
LDOC1 leucine zipper, down-regulated in cancer 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LTF lactotransferrin
MALT1 MALT1 paracaspase
MAOA monoamine oxidase A
MAPK13 mitogen-activated protein kinase 13
OLFM4 olfactomedin 4
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PNKP polynucleotide kinase 3'-phosphatase
PRKCZ protein kinase C, zeta
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFRP1 secreted frizzled-related protein 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN13 tetraspanin 13
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
BHLHE41 basic helix-loop-helix family, member e41
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BPHL biphenyl hydrolase-like (serine hydrolase)
C6ORF62 chromosome 6 open reading frame 62
CAST calpastatin
CAV2 caveolin 2
CD44 CD44 molecule (Indian blood group)
CSRP2 cysteine and glycine-rich protein 2
EGLN3 egl-9 family hypoxia-inducible factor 3
ERLIN2 ER lipid raft associated 2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
KLF4 Kruppel-like factor 4 (gut)
MAP7 microtubule-associated protein 7
MEIS1 Meis homeobox 1
MFAP5 microfibrillar associated protein 5
MSLN mesothelin
MUC16 mucin 16, cell surface associated
NVL nuclear VCP-like
PLAT plasminogen activator, tissue
PRDX2 peroxiredoxin 2
RGCC regulator of cell cycle
RIPK4 receptor-interacting serine-threonine kinase 4
SHB Src homology 2 domain containing adaptor protein B
SMNDC1 survival motor neuron domain containing 1
SPRR3 small proline-rich protein 3
STC1 stanniocalcin 1
TFRC transferrin receptor
TIMP3 TIMP metallopeptidase inhibitor 3
TOR1A torsin family 1, member A (torsin A)
TRIB2 tribbles pseudokinase 2
WNT5A wingless-type MMTV integration site family, member 5A
ZFPM2 zinc finger protein, FOG family member 2