BRD-K68191783_ALW-II-38-3_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K68191783_ALW-II-38-3_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANXA3 annexin A3
APOD apolipoprotein D
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD81 CD81 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLDN18 claudin 18
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTGF connective tissue growth factor
CTSL cathepsin L
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
FOSL1 FOS-like antigen 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HDGFRP3 hepatoma-derived growth factor, related protein 3
INHBA inhibin, beta A
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MECOM MDS1 and EVI1 complex locus
MMP12 matrix metallopeptidase 12
MT1E metallothionein 1E
MT1F metallothionein 1F
MYBPC1 myosin binding protein C, slow type
PDE4B phosphodiesterase 4B, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRAME preferentially expressed antigen in melanoma
PRSS3 protease, serine, 3
RGS2 regulator of G-protein signaling 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SOX9 SRY (sex determining region Y)-box 9
SRGN serglycin
STC1 stanniocalcin 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
STX1A syntaxin 1A (brain)
TGM2 transglutaminase 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPM2 tropomyosin 2 (beta)

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CA12 carbonic anhydrase XII
CASP7 caspase 7, apoptosis-related cysteine peptidase
CORO1A coronin, actin binding protein, 1A
CRIP1 cysteine-rich protein 1 (intestinal)
CRYAB crystallin, alpha B
CX3CR1 chemokine (C-X3-C motif) receptor 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DHCR24 24-dehydrocholesterol reductase
GPX3 glutathione peroxidase 3
IGFBP6 insulin-like growth factor binding protein 6
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
NID1 nidogen 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PLA2G16 phospholipase A2, group XVI
QPRT quinolinate phosphoribosyltransferase
RET ret proto-oncogene
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
THBS2 thrombospondin 2
TTC39A tetratricopeptide repeat domain 39A
TUBB2A tubulin, beta 2A class IIa
TUSC3 tumor suppressor candidate 3
UGDH UDP-glucose 6-dehydrogenase
VCAN versican
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon