BRD-K68185022_Ursolic Acid_MCF7_6.0_h_70.07_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K68185022_Ursolic Acid_MCF7_6.0_h_70.07_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ATF3 activating transcription factor 3
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CXADR coxsackie virus and adenovirus receptor
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
FN1 fibronectin 1
FOXO3 forkhead box O3
GATA6 GATA binding protein 6
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER3 immediate early response 3
INSIG1 insulin induced gene 1
JAG1 jagged 1
KLF5 Kruppel-like factor 5 (intestinal)
KRT15 keratin 15, type I
LDLR low density lipoprotein receptor
LGALS4 lectin, galactoside-binding, soluble, 4
MSMO1 methylsterol monooxygenase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEB nebulin
PEG3 paternally expressed 3
PHLDA2 pleckstrin homology-like domain, family A, member 2
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A14 S100 calcium binding protein A14
S100P S100 calcium binding protein P
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SHB Src homology 2 domain containing adaptor protein B
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SNAI2 snail family zinc finger 2
THBS1 thrombospondin 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BMI1 BMI1 proto-oncogene, polycomb ring finger
CD59 CD59 molecule, complement regulatory protein
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
HACD2 3-hydroxyacyl-CoA dehydratase 2
HLTF helicase-like transcription factor
HOXC6 homeobox C6
MSX1 msh homeobox 1
NPR3 natriuretic peptide receptor 3
NPY neuropeptide Y
OLFM1 olfactomedin 1
PTDSS1 phosphatidylserine synthase 1
RNF167 ring finger protein 167
RPS4Y1 ribosomal protein S4, Y-linked 1
SFPQ splicing factor proline/glutamine-rich