BRD-K68185022_Ursolic Acid_MCF7_24.0_h_70.07_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K68185022_Ursolic Acid_MCF7_24.0_h_70.07_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADGRE5 adhesion G protein-coupled receptor E5
ANXA1 annexin A1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BHLHE40 basic helix-loop-helix family, member e40
BMP2 bone morphogenetic protein 2
C8ORF4 chromosome 8 open reading frame 4
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DEFA4 defensin, alpha 4, corticostatin
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADS3 fatty acid desaturase 3
FNDC3B fibronectin type III domain containing 3B
FOSL1 FOS-like antigen 1
GAGE3 G antigen 3
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
JAG1 jagged 1
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
MAOB monoamine oxidase B
MME membrane metallo-endopeptidase
MTSS1 metastasis suppressor 1
MX1 MX dynamin-like GTPase 1
NFE2L3 nuclear factor, erythroid 2-like 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PLAU plasminogen activator, urokinase
PPAP2A phosphatidic acid phosphatase type 2A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS2 regulator of G-protein signaling 2
SIK1 salt-inducible kinase 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SRGN serglycin
TGFA transforming growth factor, alpha
TGFBI transforming growth factor, beta-induced, 68kDa
TKTL1 transketolase-like 1
TSPAN8 tetraspanin 8
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BEX1 brain expressed, X-linked 1
CA12 carbonic anhydrase XII
CCNG1 cyclin G1
CHMP4A charged multivesicular body protein 4A
CRABP2 cellular retinoic acid binding protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
DDB2 damage-specific DNA binding protein 2, 48kDa
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
FXYD2 FXYD domain containing ion transport regulator 2
GAS1 growth arrest-specific 1
GJA1 gap junction protein, alpha 1, 43kDa
HIST1H2BK histone cluster 1, H2bk
IGSF3 immunoglobulin superfamily, member 3
ISOC1 isochorismatase domain containing 1
KIAA0101 KIAA0101
KYNU kynureninase
METTL9 methyltransferase like 9
MSRB2 methionine sulfoxide reductase B2
MUC1 mucin 1, cell surface associated
MYH10 myosin, heavy chain 10, non-muscle
NME4 NME/NM23 nucleoside diphosphate kinase 4
NUSAP1 nucleolar and spindle associated protein 1
PFN2 profilin 2
PODXL podocalyxin-like
RAB25 RAB25, member RAS oncogene family
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TBC1D16 TBC1 domain family, member 16
UBL3 ubiquitin-like 3