BRD-K68143200_NSC 95397_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K68143200_NSC 95397_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
CA1 carbonic anhydrase I
CD163 CD163 molecule
CLCA4 chloride channel accessory 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
FBLN1 fibulin 1
GATA3 GATA binding protein 3
GCLM glutamate-cysteine ligase, modifier subunit
HAPLN1 hyaluronan and proteoglycan link protein 1
HBB hemoglobin, beta
HBD hemoglobin, delta
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPB8 heat shock 22kDa protein 8
IER5 immediate early response 5
KIAA0226L KIAA0226-like
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
PPAP2B phosphatidic acid phosphatase type 2B
RHOBTB3 Rho-related BTB domain containing 3
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
TPD52L1 tumor protein D52-like 1
TUBB2A tubulin, beta 2A class IIa
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
C2CD5 C2 calcium-dependent domain containing 5
HP haptoglobin
IFRD2 interferon-related developmental regulator 2
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
KRT14 keratin 14, type I
LCN2 lipocalin 2
MET MET proto-oncogene, receptor tyrosine kinase
SQRDL sulfide quinone reductase-like (yeast)
TM4SF1 transmembrane 4 L six family member 1
TNS3 tensin 3
ZNF185 zinc finger protein 185 (LIM domain)