BRD-K68143200_NSC 95397_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K68143200_NSC 95397_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DCN decorin
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DSP desmoplakin
EMP1 epithelial membrane protein 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FZD10 frizzled class receptor 10
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GPRC5A G protein-coupled receptor, class C, group 5, member A
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP5 insulin-like growth factor binding protein 5
KLF4 Kruppel-like factor 4 (gut)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
S100A8 S100 calcium binding protein A8
SPARCL1 SPARC-like 1 (hevin)
STAR steroidogenic acute regulatory protein
TMEM45A transmembrane protein 45A
ZFAND5 zinc finger, AN1-type domain 5
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ASPH aspartate beta-hydroxylase
FOLR1 folate receptor 1 (adult)
FSTL1 follistatin-like 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
ITGA6 integrin, alpha 6
MET MET proto-oncogene, receptor tyrosine kinase
MLPH melanophilin
PTP4A2 protein tyrosine phosphatase type IVA, member 2
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)