BRD-K67868012_PI-103_HS578T_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-K67868012_PI-103_HS578T_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADD3 adducin 3 (gamma)
ANKRD36B ankyrin repeat domain 36B
BPGM 2,3-bisphosphoglycerate mutase
C6ORF48 chromosome 6 open reading frame 48
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CDC42 cell division cycle 42
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DAPK1 death-associated protein kinase 1
DCN decorin
DUSP6 dual specificity phosphatase 6
EAPP E2F-associated phosphoprotein
EFNB2 ephrin-B2
EYA2 EYA transcriptional coactivator and phosphatase 2
FGFR1 fibroblast growth factor receptor 1
FOXO4 forkhead box O4
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GAS1 growth arrest-specific 1
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GPC4 glypican 4
HBP1 HMG-box transcription factor 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HMOX1 heme oxygenase 1
IGKC immunoglobulin kappa constant
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM3A lysine (K)-specific demethylase 3A
KLF6 Kruppel-like factor 6
PAN2 PAN2 poly(A) specific ribonuclease subunit
PLAT plasminogen activator, tissue
PSAP prosaposin
PTN pleiotrophin
RPL38 ribosomal protein L38
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SOX4 SRY (sex determining region Y)-box 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAR steroidogenic acute regulatory protein
STX1A syntaxin 1A (brain)
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPR translocated promoter region, nuclear basket protein
VCAM1 vascular cell adhesion molecule 1
ZC3H15 zinc finger CCCH-type containing 15
ZNF292 zinc finger protein 292

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABAT 4-aminobutyrate aminotransferase
ALB albumin
APOH apolipoprotein H (beta-2-glycoprotein I)
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL2 chemokine (C-C motif) ligand 2
CDC25A cell division cycle 25A
CLIC5 chloride intracellular channel 5
CTSZ cathepsin Z
CXADR coxsackie virus and adenovirus receptor
DDIT4 DNA-damage-inducible transcript 4
DERA deoxyribose-phosphate aldolase (putative)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP14 dual specificity phosphatase 14
ECM1 extracellular matrix protein 1
FGA fibrinogen alpha chain
FGFR3 fibroblast growth factor receptor 3
FOSL1 FOS-like antigen 1
GADD45B growth arrest and DNA-damage-inducible, beta
GNAS GNAS complex locus
GRIA2 glutamate receptor, ionotropic, AMPA 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOPX HOP homeobox
HSPA1A heat shock 70kDa protein 1A
KLK10 kallikrein-related peptidase 10
LAMA3 laminin, alpha 3
MAT2A methionine adenosyltransferase II, alpha
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PI3 peptidase inhibitor 3, skin-derived
PLAC8 placenta-specific 8
RGCC regulator of cell cycle
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RTN1 reticulon 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLPI secretory leukocyte peptidase inhibitor
SNX10 sorting nexin 10
TACSTD2 tumor-associated calcium signal transducer 2
TDO2 tryptophan 2,3-dioxygenase
TWF1 twinfilin actin binding protein 1