BRD-K67808578_1391-0741_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-K67808578_1391-0741_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
CDC25B cell division cycle 25B
CTSL cathepsin L
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
HLA-B major histocompatibility complex, class I, B
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
KDM5D lysine (K)-specific demethylase 5D
KLF2 Kruppel-like factor 2
LRP4 low density lipoprotein receptor-related protein 4
MCUR1 mitochondrial calcium uniporter regulator 1
MMP1 matrix metallopeptidase 1
MMP7 matrix metallopeptidase 7
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NPY1R neuropeptide Y receptor Y1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PNP purine nucleoside phosphorylase
RPS4Y1 ribosomal protein S4, Y-linked 1
TGM2 transglutaminase 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM176B transmembrane protein 176B
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL4 acyl-CoA synthetase long-chain family member 4
ANXA3 annexin A3
ASNS asparagine synthetase (glutamine-hydrolyzing)
AUTS2 autism susceptibility candidate 2
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
CLC Charcot-Leyden crystal galectin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELANE elastase, neutrophil expressed
ENC1 ectodermal-neural cortex 1 (with BTB domain)
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
KRT23 keratin 23, type I
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NBEA neurobeachin
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
PDE10A phosphodiesterase 10A
PON3 paraoxonase 3
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
SCGB1D2 secretoglobin, family 1D, member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
VTCN1 V-set domain containing T cell activation inhibitor 1