BRD-K67808578_1391-0741_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

24 genes differentially expressed following the BRD-K67808578_1391-0741_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C3ORF14 chromosome 3 open reading frame 14
GREM1 gremlin 1, DAN family BMP antagonist
IFI6 interferon, alpha-inducible protein 6
JCHAIN joining chain of multimeric IgA and IgM
LDOC1 leucine zipper, down-regulated in cancer 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SCG5 secretogranin V
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP3 aquaporin 3 (Gill blood group)
CA12 carbonic anhydrase XII
COL4A2 collagen, type IV, alpha 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FXYD3 FXYD domain containing ion transport regulator 3
GATA3 GATA binding protein 3
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
IQGAP1 IQ motif containing GTPase activating protein 1
LCN2 lipocalin 2
S100P S100 calcium binding protein P
SOX4 SRY (sex determining region Y)-box 4
TACSTD2 tumor-associated calcium signal transducer 2