BRD-K67808578_1391-0741_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

89 genes differentially expressed following the BRD-K67808578_1391-0741_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACKR3 atypical chemokine receptor 3
ANXA4 annexin A4
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX4 brain expressed, X-linked 4
BPHL biphenyl hydrolase-like (serine hydrolase)
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
DDIT4 DNA-damage-inducible transcript 4
EFNA1 ephrin-A1
FCGBP Fc fragment of IgG binding protein
GLUL glutamate-ammonia ligase
GSDMB gasdermin B
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H3H histone cluster 1, H3h
HOXA10 homeobox A10
IL1R1 interleukin 1 receptor, type I
IVNS1ABP influenza virus NS1A binding protein
LGALS2 lectin, galactoside-binding, soluble, 2
MXI1 MAX interactor 1, dimerization protein
MYRF myelin regulatory factor
NDRG1 N-myc downstream regulated 1
PHGDH phosphoglycerate dehydrogenase
PLXNB2 plexin B2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RTN2 reticulon 2
SELENBP1 selenium binding protein 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
STXBP2 syntaxin binding protein 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNT1 troponin T type 1 (skeletal, slow)
TST thiosulfate sulfurtransferase (rhodanese)
TYMP thymidine phosphorylase
VEGFA vascular endothelial growth factor A
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AXL AXL receptor tyrosine kinase
CAV2 caveolin 2
CCNA2 cyclin A2
CDC25A cell division cycle 25A
CDKN3 cyclin-dependent kinase inhibitor 3
CENPU centromere protein U
CSRP2 cysteine and glycine-rich protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP14 dual specificity phosphatase 14
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GNAS GNAS complex locus
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HN1 hematological and neurological expressed 1
IGFBP3 insulin-like growth factor binding protein 3
KDM5D lysine (K)-specific demethylase 5D
KIF20A kinesin family member 20A
KRT14 keratin 14, type I
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
LAMC1 laminin, gamma 1 (formerly LAMB2)
LIPA lipase A, lysosomal acid, cholesterol esterase
MAP2K3 mitogen-activated protein kinase kinase 3
NAV3 neuron navigator 3
NR1D2 nuclear receptor subfamily 1, group D, member 2
OXTR oxytocin receptor
PBK PDZ binding kinase
PLAGL1 pleiomorphic adenoma gene-like 1
S100A2 S100 calcium binding protein A2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SLIT2 slit homolog 2 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
STMN1 stathmin 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TOP2A topoisomerase (DNA) II alpha 170kDa
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1