BRD-K67619794_2,6-difluoro-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzamide_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K67619794_2,6-difluoro-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzamide_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CDH3 cadherin 3, type 1, P-cadherin (placental)
IFI6 interferon, alpha-inducible protein 6
NPY neuropeptide Y
PDLIM5 PDZ and LIM domain 5
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TMPRSS2 transmembrane protease, serine 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ARL4C ADP-ribosylation factor-like 4C
CPA3 carboxypeptidase A3 (mast cell)
CREB1 cAMP responsive element binding protein 1
DHCR7 7-dehydrocholesterol reductase
GSTZ1 glutathione S-transferase zeta 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LGALS8 lectin, galactoside-binding, soluble, 8
MMP2 matrix metallopeptidase 2
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQLE squalene epoxidase
TNNT1 troponin T type 1 (skeletal, slow)