BRD-K67619794_2,6-difluoro-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzamide_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

24 genes differentially expressed following the BRD-K67619794_2,6-difluoro-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzamide_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
CLCN3 chloride channel, voltage-sensitive 3
CNPY3 canopy FGF signaling regulator 3
CYB561 cytochrome b561
FXYD3 FXYD domain containing ion transport regulator 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
KLK6 kallikrein-related peptidase 6
PIEZO2 piezo-type mechanosensitive ion channel component 2
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBM47 RNA binding motif protein 47
SLPI secretory leukocyte peptidase inhibitor
TGM2 transglutaminase 2
TRIM16 tripartite motif containing 16

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
ARMCX2 armadillo repeat containing, X-linked 2
CPE carboxypeptidase E
DPT dermatopontin
FST follistatin
HIST1H2BG histone cluster 1, H2bg
MT1F metallothionein 1F
PCP4 Purkinje cell protein 4
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
SULF1 sulfatase 1
TGFB3 transforming growth factor, beta 3
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