BRD-K67010098_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

100 genes differentially expressed following the BRD-K67010098_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADO 2-aminoethanethiol (cysteamine) dioxygenase
BASP1 brain abundant, membrane attached signal protein 1
BEX1 brain expressed, X-linked 1
CCL19 chemokine (C-C motif) ligand 19
CCND1 cyclin D1
CCR7 chemokine (C-C motif) receptor 7
CLIC4 chloride intracellular channel 4
CLU clusterin
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL14 chemokine (C-X-C motif) ligand 14
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DSP desmoplakin
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FYB FYN binding protein
GSTZ1 glutathione S-transferase zeta 1
HAL histidine ammonia-lyase
HES1 hes family bHLH transcription factor 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIAA0101 KIAA0101
KRT7 keratin 7, type II
LAMP5 lysosomal-associated membrane protein family, member 5
MAP7 microtubule-associated protein 7
MARCKSL1 MARCKS-like 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PPIF peptidylprolyl isomerase F
QPCT glutaminyl-peptide cyclotransferase
RAB9A RAB9A, member RAS oncogene family
S100A12 S100 calcium binding protein A12
S100P S100 calcium binding protein P
SELL selectin L
SIAH2 siah E3 ubiquitin protein ligase 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SMS spermine synthase
SORD sorbitol dehydrogenase
SOX9 SRY (sex determining region Y)-box 9
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TSPAN8 tetraspanin 8
UBE2A ubiquitin-conjugating enzyme E2A
XPO7 exportin 7

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AEBP1 AE binding protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ARMCX2 armadillo repeat containing, X-linked 2
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD52 CD52 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CHRDL1 chordin-like 1
CPE carboxypeptidase E
DCHS1 dachsous cadherin-related 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
EPHA4 EPH receptor A4
FGFBP1 fibroblast growth factor binding protein 1
FHL1 four and a half LIM domains 1
FXYD6 FXYD domain containing ion transport regulator 6
G0S2 G0/G1 switch 2
GATA6 GATA binding protein 6
GPX3 glutathione peroxidase 3
HILPDA hypoxia inducible lipid droplet-associated
HIST1H2BD histone cluster 1, H2bd
HSPA2 heat shock 70kDa protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LOC100505650 uncharacterized LOC100505650
MEIS2 Meis homeobox 2
MGP matrix Gla protein
NEB nebulin
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PEG3 paternally expressed 3
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
RGCC regulator of cell cycle
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SHB Src homology 2 domain containing adaptor protein B
SLC38A1 solute carrier family 38, member 1
SULF1 sulfatase 1
SUSD4 sushi domain containing 4
TACC2 transforming, acidic coiled-coil containing protein 2
TFPI2 tissue factor pathway inhibitor 2
TNNT1 troponin T type 1 (skeletal, slow)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VTCN1 V-set domain containing T cell activation inhibitor 1
VWF von Willebrand factor
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)