BRD-K65182930_NVP-AUY922_MCF7_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K65182930_NVP-AUY922_MCF7_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ARG2 arginase 2
BHLHE41 basic helix-loop-helix family, member e41
CCL5 chemokine (C-C motif) ligand 5
CHN1 chimerin 1
COL9A2 collagen, type IX, alpha 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FN1 fibronectin 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BG histone cluster 1, H2bg
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IFI27 interferon, alpha-inducible protein 27
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLV3-19 immunoglobulin lambda variable 3-19
LY75 lymphocyte antigen 75
MBNL2 muscleblind-like splicing regulator 2
MDK midkine (neurite growth-promoting factor 2)
MICALL1 MICAL-like 1
MME membrane metallo-endopeptidase
NKX3-1 NK3 homeobox 1
PDIA5 protein disulfide isomerase family A, member 5
PRKCH protein kinase C, eta
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPON1 spondin 1, extracellular matrix protein
TMEM30B transmembrane protein 30B
TRBC1 T cell receptor beta constant 1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
APOD apolipoprotein D
CD36 CD36 molecule (thrombospondin receptor)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
DAPK1 death-associated protein kinase 1
EIF5A eukaryotic translation initiation factor 5A
FAS Fas cell surface death receptor
FLRT2 fibronectin leucine rich transmembrane protein 2
FYN FYN proto-oncogene, Src family tyrosine kinase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
HBB hemoglobin, beta
ITGA6 integrin, alpha 6
LAPTM4B lysosomal protein transmembrane 4 beta
MGLL monoglyceride lipase
MMP7 matrix metallopeptidase 7
MTERF3 mitochondrial transcription termination factor 3
MYLK myosin light chain kinase
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PLAGL1 pleiomorphic adenoma gene-like 1
PLIN1 perilipin 1
RAD51C RAD51 paralog C
RGS13 regulator of G-protein signaling 13
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SATB1 SATB homeobox 1
SFRP1 secreted frizzled-related protein 1
SPP1 secreted phosphoprotein 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
VCAN versican
ZDHHC6 zinc finger, DHHC-type containing 6