BRD-K65182930_NVP-AUY922_HS578T_3_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K65182930_NVP-AUY922_HS578T_3_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOE apolipoprotein E
BAG3 BCL2-associated athanogene 3
C1QA complement component 1, q subcomponent, A chain
CACYBP calcyclin binding protein
CD40 CD40 molecule, TNF receptor superfamily member 5
COL2A1 collagen, type II, alpha 1
COL9A3 collagen, type IX, alpha 3
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
FGFR2 fibroblast growth factor receptor 2
GLUL glutamate-ammonia ligase
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
IGKC immunoglobulin kappa constant
JUN jun proto-oncogene
KRT13 keratin 13, type I
LYZ lysozyme
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NLGN4X neuroligin 4, X-linked
RPL31 ribosomal protein L31
SFTPC surfactant protein C
SGK1 serum/glucocorticoid regulated kinase 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADRB2 adrenoceptor beta 2, surface
AREG amphiregulin
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CREB1 cAMP responsive element binding protein 1
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
HES1 hes family bHLH transcription factor 1
IER3 immediate early response 3
MAP1B microtubule-associated protein 1B
MAPT microtubule-associated protein tau
MYOF myoferlin
OXTR oxytocin receptor
PLAT plasminogen activator, tissue
PNMA2 paraneoplastic Ma antigen 2
PTX3 pentraxin 3, long
SATB2 SATB homeobox 2
SFRP1 secreted frizzled-related protein 1
SNAP25 synaptosomal-associated protein, 25kDa
VCAN versican