BRD-K65148867_4-(tert-butyl)-N-(5-chloro-2-(1H-tetrazol-5-yl)phenyl)benzamide KUC107303N_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-K65148867_4-(tert-butyl)-N-(5-chloro-2-(1H-tetrazol-5-yl)phenyl)benzamide KUC107303N_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL4 chemokine (C-C motif) ligand 4
CCNA1 cyclin A1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL4A5 collagen, type IV, alpha 5
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
EREG epiregulin
FST follistatin
HCAR3 hydroxycarboxylic acid receptor 3
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
MMP12 matrix metallopeptidase 12
MYB v-myb avian myeloblastosis viral oncogene homolog
NQO1 NAD(P)H dehydrogenase, quinone 1
PI3 peptidase inhibitor 3, skin-derived
RPL37A ribosomal protein L37a
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TFF3 trefoil factor 3 (intestinal)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TOX3 TOX high mobility group box family member 3
WLS wntless Wnt ligand secretion mediator
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
FLRT3 fibronectin leucine rich transmembrane protein 3
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
NEFL neurofilament, light polypeptide
RGS2 regulator of G-protein signaling 2
TFPI2 tissue factor pathway inhibitor 2
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)