BRD-K64857848_XMD-885_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K64857848_XMD-885_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
BEX1 brain expressed, X-linked 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
GALC galactosylceramidase
GBE1 glucan (1,4-alpha-), branching enzyme 1
GDF15 growth differentiation factor 15
HCP5 HLA complex P5 (non-protein coding)
HHEX hematopoietically expressed homeobox
HIST1H1C histone cluster 1, H1c
HIST1H2BC histone cluster 1, H2bc
HIST2H2BE histone cluster 2, H2be
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IGFBP1 insulin-like growth factor binding protein 1
LTF lactotransferrin
LXN latexin
LYZ lysozyme
MBTPS1 membrane-bound transcription factor peptidase, site 1
MMP7 matrix metallopeptidase 7
MT1E metallothionein 1E
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
MT2A metallothionein 2A
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
OAT ornithine aminotransferase
PHYH phytanoyl-CoA 2-hydroxylase
PLIN2 perilipin 2
POSTN periostin, osteoblast specific factor
PRAME preferentially expressed antigen in melanoma
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTX3 pentraxin 3, long
QPCT glutaminyl-peptide cyclotransferase
RIOK3 RIO kinase 3
RTN1 reticulon 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SPTBN1 spectrin, beta, non-erythrocytic 1
SRGN serglycin
STOM stomatin
TMEM110 transmembrane protein 110
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPYL5 TSPY-like 5
VLDLR very low density lipoprotein receptor

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
CAPN1 calpain 1, (mu/I) large subunit
CBX1 chromobox homolog 1
CCDC86 coiled-coil domain containing 86
CDA cytidine deaminase
CHIC2 cysteine-rich hydrophobic domain 2
COL5A1 collagen, type V, alpha 1
CPE carboxypeptidase E
CTSZ cathepsin Z
DHRS2 dehydrogenase/reductase (SDR family) member 2
DICER1 dicer 1, ribonuclease type III
EGFR epidermal growth factor receptor
EIF5 eukaryotic translation initiation factor 5
FGFBP1 fibroblast growth factor binding protein 1
FLRT2 fibronectin leucine rich transmembrane protein 2
HELLS helicase, lymphoid-specific
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
ICAM3 intercellular adhesion molecule 3
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KIF14 kinesin family member 14
KRT17 keratin 17, type I
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAL mal, T-cell differentiation protein
PGAM1 phosphoglycerate mutase 1 (brain)
PLBD1 phospholipase B domain containing 1
PLXNB2 plexin B2
PMM2 phosphomannomutase 2
S100A9 S100 calcium binding protein A9
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC38A1 solute carrier family 38, member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SPON1 spondin 1, extracellular matrix protein
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TPBG trophoblast glycoprotein