BRD-K64857848_XMD-885_A375_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

97 genes differentially expressed following the BRD-K64857848_XMD-885_A375_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDOA aldolase A, fructose-bisphosphate
AQP1 aquaporin 1 (Colton blood group)
ARMCX2 armadillo repeat containing, X-linked 2
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
CAPG capping protein (actin filament), gelsolin-like
CD99 CD99 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHRDL1 chordin-like 1
CKB creatine kinase, brain
CLU clusterin
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CTSD cathepsin D
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
ETV1 ets variant 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FMOD fibromodulin
G0S2 G0/G1 switch 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H2AC histone cluster 1, H2ac
HOPX HOP homeobox
KRT15 keratin 15, type I
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LAMP3 lysosomal-associated membrane protein 3
LEPR leptin receptor
METRN meteorin, glial cell differentiation regulator
NQO1 NAD(P)H dehydrogenase, quinone 1
OAT ornithine aminotransferase
PDE4B phosphodiesterase 4B, cAMP-specific
PPAP2B phosphatidic acid phosphatase type 2B
RGCC regulator of cell cycle
RPL37A ribosomal protein L37a
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SQSTM1 sequestosome 1
TACSTD2 tumor-associated calcium signal transducer 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM2 transmembrane protein 2
TMEM30B transmembrane protein 30B
TMEM47 transmembrane protein 47
TPD52L1 tumor protein D52-like 1
TUBA1A tubulin, alpha 1a
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
CARKD carbohydrate kinase domain containing
CCL20 chemokine (C-C motif) ligand 20
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
EPHA3 EPH receptor A3
FGFR3 fibroblast growth factor receptor 3
GDF15 growth differentiation factor 15
GOLGA8A golgin A8 family, member A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGL immunoglobulin lambda locus
IL1R2 interleukin 1 receptor, type II
LAMC1 laminin, gamma 1 (formerly LAMB2)
LGALS4 lectin, galactoside-binding, soluble, 4
LOXL2 lysyl oxidase-like 2
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA5 melanoma antigen family A5
MAGEA6 melanoma antigen family A6
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MGAM maltase-glucoamylase
MRPS30 mitochondrial ribosomal protein S30
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
P3H2 prolyl 3-hydroxylase 2
POSTN periostin, osteoblast specific factor
PSAT1 phosphoserine aminotransferase 1
PXDN peroxidasin
PYCR1 pyrroline-5-carboxylate reductase 1
S100P S100 calcium binding protein P
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SNX7 sorting nexin 7
SORBS3 sorbin and SH3 domain containing 3
SPINK1 serine peptidase inhibitor, Kazal type 1
TEX10 testis expressed 10
TRIB3 tribbles pseudokinase 3
USP34 ubiquitin specific peptidase 34
WBP5 WW domain binding protein 5