BRD-K64800655_PHA-793887_LNCAP_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

134 genes differentially expressed following the BRD-K64800655_PHA-793887_LNCAP_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG2 actin, gamma 2, smooth muscle, enteric
AMIGO2 adhesion molecule with Ig-like domain 2
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CCL20 chemokine (C-C motif) ligand 20
CNN1 calponin 1, basic, smooth muscle
COL1A2 collagen, type I, alpha 2
COL5A2 collagen, type V, alpha 2
COL6A3 collagen, type VI, alpha 3
CP ceruloplasmin (ferroxidase)
CRYAB crystallin, alpha B
CTSV cathepsin V
DLK1 delta-like 1 homolog (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DST dystonin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
GPM6A glycoprotein M6A
HBE1 hemoglobin, epsilon 1
HOXC6 homeobox C6
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGFBP5 insulin-like growth factor binding protein 5
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT8 keratin 8, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMO3 LIM domain only 3 (rhombotin-like 2)
MAP1B microtubule-associated protein 1B
MUC1 mucin 1, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYLK myosin light chain kinase
NTS neurotensin
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PLAT plasminogen activator, tissue
PLCB4 phospholipase C, beta 4
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POSTN periostin, osteoblast specific factor
PPAP2C phosphatidic acid phosphatase type 2C
PRAME preferentially expressed antigen in melanoma
PRKCB protein kinase C, beta
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPAG4 sperm associated antigen 4
STS steroid sulfatase (microsomal), isozyme S
TFRC transferrin receptor
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRH thyrotropin-releasing hormone
TUSC3 tumor suppressor candidate 3
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ANXA3 annexin A3
ARID4B AT rich interactive domain 4B (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4C ADP-ribosylation factor-like 4C
AURKA aurora kinase A
AURKB aurora kinase B
AVPI1 arginine vasopressin-induced 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAG5 BCL2-associated athanogene 5
BASP1 brain abundant, membrane attached signal protein 1
BTG1 B-cell translocation gene 1, anti-proliferative
CBR3 carbonyl reductase 3
CCNE2 cyclin E2
CCNF cyclin F
CD24 CD24 molecule
CDC25A cell division cycle 25A
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHD7 chromodomain helicase DNA binding protein 7
CKS2 CDC28 protein kinase regulatory subunit 2
CLC Charcot-Leyden crystal galectin
CXCL13 chemokine (C-X-C motif) ligand 13
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPT dermatopontin
DUSP1 dual specificity phosphatase 1
EIF5 eukaryotic translation initiation factor 5
ELANE elastase, neutrophil expressed
EPAS1 endothelial PAS domain protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FOSL1 FOS-like antigen 1
GATA2 GATA binding protein 2
GPNMB glycoprotein (transmembrane) nmb
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HHEX hematopoietically expressed homeobox
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
IGFBP6 insulin-like growth factor binding protein 6
KEAP1 kelch-like ECH-associated protein 1
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MED17 mediator complex subunit 17
MID1IP1 MID1 interacting protein 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
PERP PERP, TP53 apoptosis effector
RHOB ras homolog family member B
RND3 Rho family GTPase 3
S100P S100 calcium binding protein P
SLC38A2 solute carrier family 38, member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD1 SMAD family member 1
SRGN serglycin
TARP TCR gamma alternate reading frame protein
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGIF1 TGFB-induced factor homeobox 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TPSB2 tryptase beta 2 (gene/pseudogene)
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF232 zinc finger protein 232