BRD-K64800655_PHA-793887_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

115 genes differentially expressed following the BRD-K64800655_PHA-793887_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
C1ORF116 chromosome 1 open reading frame 116
CADM1 cell adhesion molecule 1
CD300A CD300a molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
DPP4 dipeptidyl-peptidase 4
DSP desmoplakin
EZR ezrin
FAM46A family with sequence similarity 46, member A
FHL2 four and a half LIM domains 2
GLS glutaminase
GPRC5A G protein-coupled receptor, class C, group 5, member A
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HPSE heparanase
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB8 heat shock 22kDa protein 8
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
INPP1 inositol polyphosphate-1-phosphatase
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNK3 potassium channel, two pore domain subfamily K, member 3
KRT7 keratin 7, type II
KRT81 keratin 81, type II
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MXRA7 matrix-remodelling associated 7
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
ODC1 ornithine decarboxylase 1
PDZK1IP1 PDZK1 interacting protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRKCH protein kinase C, eta
PRSS3 protease, serine, 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX3 runt-related transcription factor 3
S100A7 S100 calcium binding protein A7
SMAD3 SMAD family member 3
SNX11 sorting nexin 11
SOX9 SRY (sex determining region Y)-box 9
STC1 stanniocalcin 1
TFF1 trefoil factor 1
WFS1 Wolfram syndrome 1 (wolframin)

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AURKB aurora kinase B
CA12 carbonic anhydrase XII
CBS cystathionine-beta-synthase
CCNA2 cyclin A2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLC Charcot-Leyden crystal galectin
CP ceruloplasmin (ferroxidase)
CPA3 carboxypeptidase A3 (mast cell)
CTSG cathepsin G
CXCL14 chemokine (C-X-C motif) ligand 14
DLG1 discs, large homolog 1 (Drosophila)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLK1 delta-like 1 homolog (Drosophila)
ELANE elastase, neutrophil expressed
F13A1 coagulation factor XIII, A1 polypeptide
GATA2 GATA binding protein 2
GLUL glutamate-ammonia ligase
GTPBP8 GTP-binding protein 8 (putative)
HDAC6 histone deacetylase 6
HMGB2 high mobility group box 2
HMGB3 high mobility group box 3
HP haptoglobin
HSPA2 heat shock 70kDa protein 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
KIAA0101 KIAA0101
KIF20A kinesin family member 20A
KRT19 keratin 19, type I
LBR lamin B receptor
LOXL1 lysyl oxidase-like 1
LTF lactotransferrin
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MTSS1 metastasis suppressor 1
MYH10 myosin, heavy chain 10, non-muscle
NAP1L1 nucleosome assembly protein 1-like 1
NDRG2 NDRG family member 2
NRIP1 nuclear receptor interacting protein 1
ORM1 orosomucoid 1
PGD phosphogluconate dehydrogenase
PHGDH phosphoglycerate dehydrogenase
PLBD1 phospholipase B domain containing 1
PLTP phospholipid transfer protein
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB4A RAB4A, member RAS oncogene family
RNASET2 ribonuclease T2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEPHS1 selenophosphate synthetase 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMC4 structural maintenance of chromosomes 4
SOD2 superoxide dismutase 2, mitochondrial
STMN1 stathmin 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TCF4 transcription factor 4
TYMS thymidylate synthetase
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
XIST X inactive specific transcript (non-protein coding)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon