BRD-K64800655_PHA-793887_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K64800655_PHA-793887_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD6 abhydrolase domain containing 6
AEBP1 AE binding protein 1
ALCAM activated leukocyte cell adhesion molecule
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
C2CD2L C2CD2-like
CCL21 chemokine (C-C motif) ligand 21
CDK6 cyclin-dependent kinase 6
CP ceruloplasmin (ferroxidase)
CRIP1 cysteine-rich protein 1 (intestinal)
CSTA cystatin A (stefin A)
CTSH cathepsin H
DKK3 dickkopf WNT signaling pathway inhibitor 3
EDNRA endothelin receptor type A
ENO2 enolase 2 (gamma, neuronal)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FGG fibrinogen gamma chain
FOXO4 forkhead box O4
GCH1 GTP cyclohydrolase 1
GPC3 glypican 3
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFI27 interferon, alpha-inducible protein 27
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LIMA1 LIM domain and actin binding 1
LPAR1 lysophosphatidic acid receptor 1
LY75 lymphocyte antigen 75
MAOB monoamine oxidase B
MAP2K5 mitogen-activated protein kinase kinase 5
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
RNASE4 ribonuclease, RNase A family, 4
SATB1 SATB homeobox 1
SELL selectin L
SEPP1 selenoprotein P, plasma, 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TXNIP thioredoxin interacting protein
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28

decreased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL5 chemokine (C-X-C motif) ligand 5
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
GDF15 growth differentiation factor 15
IER5 immediate early response 5
IFRD2 interferon-related developmental regulator 2
IGL immunoglobulin lambda locus
ITGB1BP1 integrin beta 1 binding protein 1
KLK10 kallikrein-related peptidase 10
LCN2 lipocalin 2
LDHB lactate dehydrogenase B
NR4A2 nuclear receptor subfamily 4, group A, member 2
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
SGK1 serum/glucocorticoid regulated kinase 1
SRGN serglycin