BRD-K64642496_-666_NOMO1_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

178 genes differentially expressed following the BRD-K64642496_-666_NOMO1_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACKR3 atypical chemokine receptor 3
ADGRG1 adhesion G protein-coupled receptor G1
ADGRL2 adhesion G protein-coupled receptor L2
AEBP1 AE binding protein 1
ARG2 arginase 2
ARL4C ADP-ribosylation factor-like 4C
ARMCX2 armadillo repeat containing, X-linked 2
ASPN asporin
ATF3 activating transcription factor 3
BGN biglycan
BTG3 BTG family, member 3
C10ORF10 chromosome 10 open reading frame 10
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CADM1 cell adhesion molecule 1
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CAV1 caveolin 1, caveolae protein, 22kDa
CD200 CD200 molecule
CFI complement factor I
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CISD1 CDGSH iron sulfur domain 1
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
COMP cartilage oligomeric matrix protein
CPE carboxypeptidase E
CXCL10 chemokine (C-X-C motif) ligand 10
DEPTOR DEP domain containing MTOR-interacting protein
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DPP4 dipeptidyl-peptidase 4
DPYSL3 dihydropyrimidinase-like 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
FHOD3 formin homology 2 domain containing 3
FSD1 fibronectin type III and SPRY domain containing 1
FST follistatin
FXYD6 FXYD domain containing ion transport regulator 6
FZD10 frizzled class receptor 10
G0S2 G0/G1 switch 2
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
GPX3 glutathione peroxidase 3
GRK5 G protein-coupled receptor kinase 5
GSTA4 glutathione S-transferase alpha 4
GULP1 GULP, engulfment adaptor PTB domain containing 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPG2 heparan sulfate proteoglycan 2
IDO1 indoleamine 2,3-dioxygenase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1R1 interleukin 1 receptor, type I
INA internexin neuronal intermediate filament protein, alpha
INHBA inhibin, beta A
ISG15 ISG15 ubiquitin-like modifier
KCNK3 potassium channel, two pore domain subfamily K, member 3
KLK10 kallikrein-related peptidase 10
LAP3 leucine aminopeptidase 3
LMO3 LIM domain only 3 (rhombotin-like 2)
LRRC15 leucine rich repeat containing 15
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MEIS2 Meis homeobox 2
MFAP2 microfibrillar-associated protein 2
MMP2 matrix metallopeptidase 2
MN1 meningioma (disrupted in balanced translocation) 1
MX1 MX dynamin-like GTPase 1
MYH10 myosin, heavy chain 10, non-muscle
MZB1 marginal zone B and B1 cell-specific protein
NARFL nuclear prelamin A recognition factor-like
NAV2 neuron navigator 2
NEB nebulin
NEFH neurofilament, heavy polypeptide
NID2 nidogen 2 (osteonidogen)
NR2F6 nuclear receptor subfamily 2, group F, member 6
NRCAM neuronal cell adhesion molecule
OBSL1 obscurin-like 1
P3H2 prolyl 3-hydroxylase 2
PBX1 pre-B-cell leukemia homeobox 1
PDLIM3 PDZ and LIM domain 3
PEG3 paternally expressed 3
PLN phospholamban
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRUNE2 prune homolog 2 (Drosophila)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PXDN peroxidasin
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SCGB2A1 secretoglobin, family 2A, member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFRP4 secreted frizzled-related protein 4
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SNX7 sorting nexin 7
SOX17 SRY (sex determining region Y)-box 17
STK38L serine/threonine kinase 38 like
STON1 stonin 1
SULF1 sulfatase 1
TCF4 transcription factor 4
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
WARS tryptophanyl-tRNA synthetase
XIST X inactive specific transcript (non-protein coding)
ZEB1 zinc finger E-box binding homeobox 1
ZNF423 zinc finger protein 423
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACSL1 acyl-CoA synthetase long-chain family member 1
AHNAK AHNAK nucleoprotein
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATMIN ATM interactor
CA12 carbonic anhydrase XII
CCL2 chemokine (C-C motif) ligand 2
CCNE2 cyclin E2
CD99 CD99 molecule
CDK6 cyclin-dependent kinase 6
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHMP7 charged multivesicular body protein 7
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CNOT7 CCR4-NOT transcription complex, subunit 7
CSTA cystatin A (stefin A)
CXCR4 chemokine (C-X-C motif) receptor 4
CYTL1 cytokine-like 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF4B eukaryotic translation initiation factor 4B
EMP3 epithelial membrane protein 3
ERGIC3 ERGIC and golgi 3
FAM46A family with sequence similarity 46, member A
FAR2 fatty acyl CoA reductase 2
HBB hemoglobin, beta
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPA8 heat shock 70kDa protein 8
IL6R interleukin 6 receptor
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM5D lysine (K)-specific demethylase 5D
KRT14 keratin 14, type I
LITAF lipopolysaccharide-induced TNF factor
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LY75 lymphocyte antigen 75
MED1 mediator complex subunit 1
METTL7A methyltransferase like 7A
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
PI3 peptidase inhibitor 3, skin-derived
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKM pyruvate kinase, muscle
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PROM1 prominin 1
RPL36AL ribosomal protein L36a-like
RPS11 ribosomal protein S11
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RUNX3 runt-related transcription factor 3
S100B S100 calcium binding protein B
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TM9SF2 transmembrane 9 superfamily member 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TXNIP thioredoxin interacting protein
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
XPO7 exportin 7