BRD-K64634304_Retinoic acid_VCAP_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K64634304_Retinoic acid_VCAP_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ASPN asporin
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAMBI BMP and activin membrane-bound inhibitor
BLNK B-cell linker
CD163 CD163 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLEC7A C-type lectin domain family 7, member A
DUSP5 dual specificity phosphatase 5
ECM1 extracellular matrix protein 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FTH1 ferritin, heavy polypeptide 1
GCLC glutamate-cysteine ligase, catalytic subunit
HES1 hes family bHLH transcription factor 1
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB8 heat shock 22kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KIAA0226L KIAA0226-like
LEF1 lymphoid enhancer-binding factor 1
LGALS8 lectin, galactoside-binding, soluble, 8
LGMN legumain
LMO3 LIM domain only 3 (rhombotin-like 2)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN1A1 mannosidase, alpha, class 1A, member 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MOXD1 monooxygenase, DBH-like 1
MTSS1 metastasis suppressor 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OLFML2A olfactomedin-like 2A
PCP4 Purkinje cell protein 4
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLBD1 phospholipase B domain containing 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSAP prosaposin
QPCT glutaminyl-peptide cyclotransferase
RAB31 RAB31, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RYBP RING1 and YY1 binding protein
S100P S100 calcium binding protein P
SDC1 syndecan 1
SFRP4 secreted frizzled-related protein 4
STK26 serine/threonine protein kinase 26
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX3 T-box 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFBI transforming growth factor, beta-induced, 68kDa
TKT transketolase
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNC tenascin C
TSPAN13 tetraspanin 13
TXNRD1 thioredoxin reductase 1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
ASRGL1 asparaginase like 1
C3 complement component 3
C7 complement component 7
CRIP1 cysteine-rich protein 1 (intestinal)
FAS Fas cell surface death receptor
GPRC5B G protein-coupled receptor, class C, group 5, member B
IFITM2 interferon induced transmembrane protein 2
LAMA3 laminin, alpha 3
LDHB lactate dehydrogenase B
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MDK midkine (neurite growth-promoting factor 2)
MFSD10 major facilitator superfamily domain containing 10
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDZK1 PDZ domain containing 1
RELN reelin
S100A6 S100 calcium binding protein A6
SCGB2A1 secretoglobin, family 2A, member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SPEN spen family transcriptional repressor
TSPAN8 tetraspanin 8