BRD-K64634304_Retinoic acid_RMUGS_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K64634304_Retinoic acid_RMUGS_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
BAG3 BCL2-associated athanogene 3
BEX1 brain expressed, X-linked 1
BLVRB biliverdin reductase B
CA2 carbonic anhydrase II
COL1A1 collagen, type I, alpha 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FGB fibrinogen beta chain
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HHEX hematopoietically expressed homeobox
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ISLR immunoglobulin superfamily containing leucine-rich repeat
KRT13 keratin 13, type I
KRT19 keratin 19, type I
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MICB MHC class I polypeptide-related sequence B
NSDHL NAD(P) dependent steroid dehydrogenase-like
PBX3 pre-B-cell leukemia homeobox 3
PDZK1IP1 PDZK1 interacting protein 1
PROM1 prominin 1
PXMP2 peroxisomal membrane protein 2, 22kDa
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A8 S100 calcium binding protein A8
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SRGN serglycin
STC1 stanniocalcin 1
TGM2 transglutaminase 2
TM4SF4 transmembrane 4 L six family member 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AMIGO2 adhesion molecule with Ig-like domain 2
APOD apolipoprotein D
ARMCX2 armadillo repeat containing, X-linked 2
AUTS2 autism susceptibility candidate 2
BCL6 B-cell CLL/lymphoma 6
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CKB creatine kinase, brain
CLDN3 claudin 3
CLIC5 chloride intracellular channel 5
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL14 chemokine (C-X-C motif) ligand 14
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FABP4 fatty acid binding protein 4, adipocyte
GBAS glioblastoma amplified sequence
GEM GTP binding protein overexpressed in skeletal muscle
GNAS GNAS complex locus
GPM6B glycoprotein M6B
GPRC5B G protein-coupled receptor, class C, group 5, member B
GSN gelsolin
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
ITM2A integral membrane protein 2A
JAG1 jagged 1
KRT17 keratin 17, type I
LTF lactotransferrin
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFIB nuclear factor I/B
PDLIM3 PDZ and LIM domain 3
PEG10 paternally expressed 10
PFN2 profilin 2
POSTN periostin, osteoblast specific factor
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTN pleiotrophin
RGS5 regulator of G-protein signaling 5
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB2A2 secretoglobin, family 2A, member 2
SHB Src homology 2 domain containing adaptor protein B
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNNC1 troponin C type 1 (slow)
TNS3 tensin 3
TOX thymocyte selection-associated high mobility group box
XBP1 X-box binding protein 1