BRD-K64634304_Retinoic acid_MCF7_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K64634304_Retinoic acid_MCF7_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARL4C ADP-ribosylation factor-like 4C
AUTS2 autism susceptibility candidate 2
BHLHE41 basic helix-loop-helix family, member e41
CCL5 chemokine (C-C motif) ligand 5
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DACH1 dachshund family transcription factor 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DUSP4 dual specificity phosphatase 4
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL1R2 interleukin 1 receptor, type II
KCNK3 potassium channel, two pore domain subfamily K, member 3
KRT13 keratin 13, type I
KRT4 keratin 4, type II
LAMA3 laminin, alpha 3
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
NQO1 NAD(P)H dehydrogenase, quinone 1
NT5E 5'-nucleotidase, ecto (CD73)
PERP PERP, TP53 apoptosis effector
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGCC regulator of cell cycle
RND3 Rho family GTPase 3
RNF167 ring finger protein 167
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SIK1 salt-inducible kinase 1
SLPI secretory leukocyte peptidase inhibitor
SNAI2 snail family zinc finger 2
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STC1 stanniocalcin 1
TBX3 T-box 3
TGFA transforming growth factor, alpha
TKT transketolase
TRD T cell receptor delta locus
TRIM16 tripartite motif containing 16
TRIM29 tripartite motif containing 29
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
VEGFA vascular endothelial growth factor A
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
CXCL14 chemokine (C-X-C motif) ligand 14
FERMT2 fermitin family member 2
GNG10 guanine nucleotide binding protein (G protein), gamma 10
HAL histidine ammonia-lyase
HN1 hematological and neurological expressed 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IL13RA2 interleukin 13 receptor, alpha 2
LAPTM4B lysosomal protein transmembrane 4 beta
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
NPY neuropeptide Y
PDGFA platelet-derived growth factor alpha polypeptide
PON2 paraoxonase 2
PXDN peroxidasin
SPINK1 serine peptidase inhibitor, Kazal type 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TSPAN8 tetraspanin 8
TUBA1A tubulin, alpha 1a