BRD-K64634304_Retinoic acid_MCF7_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K64634304_Retinoic acid_MCF7_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
AZU1 azurocidin 1
BTG1 B-cell translocation gene 1, anti-proliferative
CCL5 chemokine (C-C motif) ligand 5
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEFA4 defensin, alpha 4, corticostatin
DUSP5 dual specificity phosphatase 5
EGFL6 EGF-like-domain, multiple 6
ELANE elastase, neutrophil expressed
EPAS1 endothelial PAS domain protein 1
FAM46A family with sequence similarity 46, member A
FNDC3B fibronectin type III domain containing 3B
GNLY granulysin
GPX2 glutathione peroxidase 2
GSTA1 glutathione S-transferase alpha 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HBB hemoglobin, beta
HCAR3 hydroxycarboxylic acid receptor 3
HMOX1 heme oxygenase 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
LRP4 low density lipoprotein receptor-related protein 4
NKG7 natural killer cell granule protein 7
NR0B1 nuclear receptor subfamily 0, group B, member 1
OLFM4 olfactomedin 4
PRKCD protein kinase C, delta
PRTN3 proteinase 3
RAP1GAP RAP1 GTPase activating protein
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
SFRP4 secreted frizzled-related protein 4
SMAD3 SMAD family member 3
TCF4 transcription factor 4
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TKTL1 transketolase-like 1
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
BAG3 BCL2-associated athanogene 3
C3 complement component 3
CPE carboxypeptidase E
EGR1 early growth response 1
EVL Enah/Vasp-like
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GPX3 glutathione peroxidase 3
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HSPA8 heat shock 70kDa protein 8
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
KIAA0101 KIAA0101
KRT14 keratin 14, type I
KRT23 keratin 23, type I
MSMO1 methylsterol monooxygenase 1
MSRB2 methionine sulfoxide reductase B2
MUC1 mucin 1, cell surface associated
NCK1 NCK adaptor protein 1
NUSAP1 nucleolar and spindle associated protein 1
PAM peptidylglycine alpha-amidating monooxygenase
PLK2 polo-like kinase 2
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
REEP5 receptor accessory protein 5
S100A7 S100 calcium binding protein A7
SPDEF SAM pointed domain containing ETS transcription factor
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TGFB3 transforming growth factor, beta 3
TMEM251 transmembrane protein 251
TMEM45A transmembrane protein 45A
TRPS1 trichorhinophalangeal syndrome I
TYMS thymidylate synthetase
VAT1 vesicle amine transport 1
ZWINT ZW10 interacting kinetochore protein