BRD-K64634304_Retinoic acid_HEPG2_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K64634304_Retinoic acid_HEPG2_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADAM10 ADAM metallopeptidase domain 10
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CD46 CD46 molecule, complement regulatory protein
CERS6 ceramide synthase 6
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL4A2 collagen, type IV, alpha 2
DEFA5 defensin, alpha 5, Paneth cell-specific
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HPSE heparanase
ITGA6 integrin, alpha 6
ITM2A integral membrane protein 2A
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
NQO1 NAD(P)H dehydrogenase, quinone 1
P3H2 prolyl 3-hydroxylase 2
PLBD1 phospholipase B domain containing 1
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
ST18 suppression of tumorigenicity 18, zinc finger
TES testin LIM domain protein
TGFBI transforming growth factor, beta-induced, 68kDa
TUBB2A tubulin, beta 2A class IIa
TXNRD1 thioredoxin reductase 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ACAT1 acetyl-CoA acetyltransferase 1
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALB albumin
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX2 armadillo repeat containing, X-linked 2
BCHE butyrylcholinesterase
BEX1 brain expressed, X-linked 1
CBFB core-binding factor, beta subunit
CD24 CD24 molecule
CD81 CD81 molecule
CFDP1 craniofacial development protein 1
CP ceruloplasmin (ferroxidase)
CXCL14 chemokine (C-X-C motif) ligand 14
DDAH1 dimethylarginine dimethylaminohydrolase 1
DUSP6 dual specificity phosphatase 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FHL1 four and a half LIM domains 1
GNAS GNAS complex locus
GSTM3 glutathione S-transferase mu 3 (brain)
IER3 immediate early response 3
IGFBP1 insulin-like growth factor binding protein 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KDM5D lysine (K)-specific demethylase 5D
KRT14 keratin 14, type I
KRT7 keratin 7, type II
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MXRA7 matrix-remodelling associated 7
MYH10 myosin, heavy chain 10, non-muscle
PEG10 paternally expressed 10
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIEZO2 piezo-type mechanosensitive ion channel component 2
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLLP plasmolipin
QDPR quinoid dihydropteridine reductase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
TGM4 transglutaminase 4
THBS2 thrombospondin 2
TNC tenascin C
TUBA1A tubulin, alpha 1a
VAT1 vesicle amine transport 1