BRD-K64634304_Retinoic acid_HA1E_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K64634304_Retinoic acid_HA1E_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CD163 CD163 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CTSK cathepsin K
CX3CR1 chemokine (C-X3-C motif) receptor 1
DCN decorin
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GRB7 growth factor receptor-bound protein 7
GSR glutathione reductase
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IL13RA1 interleukin 13 receptor, alpha 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP7 matrix metallopeptidase 7
ORC1 origin recognition complex, subunit 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIR pirin (iron-binding nuclear protein)
PLIN2 perilipin 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTN pleiotrophin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRIB2 tribbles pseudokinase 2
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ANXA3 annexin A3
CLIC3 chloride intracellular channel 3
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ERAP2 endoplasmic reticulum aminopeptidase 2
FHL1 four and a half LIM domains 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FUCA1 fucosidase, alpha-L- 1, tissue
KLF6 Kruppel-like factor 6
MAGED1 melanoma antigen family D1
MARCKS myristoylated alanine-rich protein kinase C substrate
MXRA7 matrix-remodelling associated 7
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NPY neuropeptide Y
RPL37A ribosomal protein L37a
TFF1 trefoil factor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TJP2 tight junction protein 2
TSPAN8 tetraspanin 8