BRD-K64052750_gefitinib_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K64052750_gefitinib_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
CXCR4 chemokine (C-X-C motif) receptor 4
HAL histidine ammonia-lyase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
LITAF lipopolysaccharide-induced TNF factor
LTBP1 latent transforming growth factor beta binding protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPP1 selenoprotein P, plasma, 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
APOD apolipoprotein D
CALD1 caldesmon 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CHGB chromogranin B
DUSP10 dual specificity phosphatase 10
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
FGFR2 fibroblast growth factor receptor 2
FOSL1 FOS-like antigen 1
GAGE3 G antigen 3
GATA3 GATA binding protein 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBEGF heparin-binding EGF-like growth factor
HOXA10 homeobox A10
IER3 immediate early response 3
IGL immunoglobulin lambda locus
ITGA6 integrin, alpha 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEF2C myocyte enhancer factor 2C
MT1E metallothionein 1E
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MX1 MX dynamin-like GTPase 1
NCAM1 neural cell adhesion molecule 1
NEFL neurofilament, light polypeptide
NT5E 5'-nucleotidase, ecto (CD73)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM4 olfactomedin 4
PDLIM5 PDZ and LIM domain 5
PROM1 prominin 1
RHOB ras homolog family member B
SNAP25 synaptosomal-associated protein, 25kDa
SOX9 SRY (sex determining region Y)-box 9
TACSTD2 tumor-associated calcium signal transducer 2