BRD-K63068307_ZSTK-474_LNCAP_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K63068307_ZSTK-474_LNCAP_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCNG1 cyclin G1
CCNG2 cyclin G2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
FCGBP Fc fragment of IgG binding protein
GAS1 growth arrest-specific 1
GBP2 guanylate binding protein 2, interferon-inducible
GOLGA8B golgin A8 family, member B
GPATCH8 G patch domain containing 8
HBP1 HMG-box transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HMGB2 high mobility group box 2
IGFBP1 insulin-like growth factor binding protein 1
KDM3A lysine (K)-specific demethylase 3A
KIF1B kinesin family member 1B
KRCC1 lysine-rich coiled-coil 1
LGALS4 lectin, galactoside-binding, soluble, 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MFAP2 microfibrillar-associated protein 2
MXI1 MAX interactor 1, dimerization protein
MYBPC1 myosin binding protein C, slow type
NLGN4X neuroligin 4, X-linked
NRIP1 nuclear receptor interacting protein 1
PBX3 pre-B-cell leukemia homeobox 3
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PEG10 paternally expressed 10
PERP PERP, TP53 apoptosis effector
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RBP1 retinol binding protein 1, cellular
RGS10 regulator of G-protein signaling 10
RIOK3 RIO kinase 3
RPS11 ribosomal protein S11
SEPP1 selenoprotein P, plasma, 1
SNAP25 synaptosomal-associated protein, 25kDa
SOX4 SRY (sex determining region Y)-box 4
STS steroid sulfatase (microsomal), isozyme S
SYT1 synaptotagmin I
THBS2 thrombospondin 2
TMEM45A transmembrane protein 45A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TXNIP thioredoxin interacting protein
VSNL1 visinin-like 1

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AREG amphiregulin
CAPN1 calpain 1, (mu/I) large subunit
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC25A cell division cycle 25A
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CST7 cystatin F (leukocystatin)
CTSH cathepsin H
CXCL14 chemokine (C-X-C motif) ligand 14
CYB5A cytochrome b5 type A (microsomal)
DDIT4 DNA-damage-inducible transcript 4
EFHD1 EF-hand domain family, member D1
FABP4 fatty acid binding protein 4, adipocyte
GPNMB glycoprotein (transmembrane) nmb
H2AFX H2A histone family, member X
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA2 heat shock 70kDa protein 2
JMJD6 jumonji domain containing 6
MAT2A methionine adenosyltransferase II, alpha
MMP9 matrix metallopeptidase 9
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PTGDS prostaglandin D2 synthase 21kDa (brain)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SOCS1 suppressor of cytokine signaling 1
TGFA transforming growth factor, alpha
TSPAN13 tetraspanin 13
TSPYL5 TSPY-like 5