BRD-K63068307_ZSTK-474_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

119 genes differentially expressed following the BRD-K63068307_ZSTK-474_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL5 acyl-CoA synthetase long-chain family member 5
ADIRF adipogenesis regulatory factor
APOD apolipoprotein D
ARHGAP29 Rho GTPase activating protein 29
ATP9A ATPase, class II, type 9A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAZ2B bromodomain adjacent to zinc finger domain, 2B
CALCOCO1 calcium binding and coiled-coil domain 1
CDK19 cyclin-dependent kinase 19
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHN2 chimerin 2
COL9A3 collagen, type IX, alpha 3
CRISP3 cysteine-rich secretory protein 3
CTSH cathepsin H
DARS aspartyl-tRNA synthetase
DYNLT3 dynein, light chain, Tctex-type 3
E2F2 E2F transcription factor 2
ECHDC2 enoyl CoA hydratase domain containing 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM13A family with sequence similarity 13, member A
FOXO4 forkhead box O4
GALC galactosylceramidase
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GSN gelsolin
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
ISG15 ISG15 ubiquitin-like modifier
KRT19 keratin 19, type I
KRT20 keratin 20, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LOC100272216 uncharacterized LOC100272216
LY75 lymphocyte antigen 75
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGED1 melanoma antigen family D1
MAPK13 mitogen-activated protein kinase 13
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBNL2 muscleblind-like splicing regulator 2
MTSS1 metastasis suppressor 1
MTUS1 microtubule associated tumor suppressor 1
MVP major vault protein
MYO6 myosin VI
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NPDC1 neural proliferation, differentiation and control, 1
NT5E 5'-nucleotidase, ecto (CD73)
NUDCD3 NudC domain containing 3
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PGK1 phosphoglycerate kinase 1
PLCB4 phospholipase C, beta 4
POF1B premature ovarian failure, 1B
PSD3 pleckstrin and Sec7 domain containing 3
QPCT glutaminyl-peptide cyclotransferase
RAP1GAP RAP1 GTPase activating protein
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100P S100 calcium binding protein P
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERF2 small EDRK-rich factor 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPATA20 spermatogenesis associated 20
SPINK1 serine peptidase inhibitor, Kazal type 1
TACSTD2 tumor-associated calcium signal transducer 2
TIMP1 TIMP metallopeptidase inhibitor 1
TOX3 TOX high mobility group box family member 3
TRAPPC6A trafficking protein particle complex 6A
TRIM2 tripartite motif containing 2
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8
TXNIP thioredoxin interacting protein
VAT1 vesicle amine transport 1
ZMYND8 zinc finger, MYND-type containing 8
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AURKA aurora kinase A
BAG2 BCL2-associated athanogene 2
BIRC5 baculoviral IAP repeat containing 5
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CCNA2 cyclin A2
CCNF cyclin F
CD2 CD2 molecule
CDC20 cell division cycle 20
CDK1 cyclin-dependent kinase 1
CHEK2 checkpoint kinase 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
COL5A1 collagen, type V, alpha 1
CSRP2 cysteine and glycine-rich protein 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EVL Enah/Vasp-like
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGFBP1 fibroblast growth factor binding protein 1
FOSL1 FOS-like antigen 1
FST follistatin
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HPRT1 hypoxanthine phosphoribosyltransferase 1
IDO1 indoleamine 2,3-dioxygenase 1
KRT5 keratin 5, type II
LTF lactotransferrin
MYLK myosin light chain kinase
NID1 nidogen 1
PPAT phosphoribosyl pyrophosphate amidotransferase
PSAT1 phosphoserine aminotransferase 1
SALL1 spalt-like transcription factor 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLIT2 slit homolog 2 (Drosophila)
SLPI secretory leukocyte peptidase inhibitor
SPRR1A small proline-rich protein 1A
TBL1X transducin (beta)-like 1X-linked
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNC tenascin C
UBE2C ubiquitin-conjugating enzyme E2C