BRD-K63068307_ZSTK-474_HME1_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K63068307_ZSTK-474_HME1_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANXA1 annexin A1
ARID4B AT rich interactive domain 4B (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
C8ORF4 chromosome 8 open reading frame 4
CBR3 carbonyl reductase 3
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEP57 centrosomal protein 57kDa
CHIC2 cysteine-rich hydrophobic domain 2
CLCA1 chloride channel accessory 1
CLEC2B C-type lectin domain family 2, member B
DKK3 dickkopf WNT signaling pathway inhibitor 3
DUSP6 dual specificity phosphatase 6
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
EPHA4 EPH receptor A4
ETV1 ets variant 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOXG1 forkhead box G1
GCC2 GRIP and coiled-coil domain containing 2
GDF15 growth differentiation factor 15
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
HAUS4 HAUS augmin-like complex, subunit 4
HBB hemoglobin, beta
HBP1 HMG-box transcription factor 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFITM1 interferon induced transmembrane protein 1
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
MTUS1 microtubule associated tumor suppressor 1
NEFL neurofilament, light polypeptide
NRGN neurogranin (protein kinase C substrate, RC3)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUPR1 nuclear protein, transcriptional regulator, 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PRKCH protein kinase C, eta
RB1CC1 RB1-inducible coiled-coil 1
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RGS5 regulator of G-protein signaling 5
RTN1 reticulon 1
SDCBP syndecan binding protein (syntenin)
SEPW1 selenoprotein W, 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SNAP25 synaptosomal-associated protein, 25kDa
SYT1 synaptotagmin I
TAC1 tachykinin, precursor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ANXA6 annexin A6
ARL4C ADP-ribosylation factor-like 4C
CCND1 cyclin D1
CCND2 cyclin D2
CDA cytidine deaminase
CDC25A cell division cycle 25A
COL4A2 collagen, type IV, alpha 2
CRIP1 cysteine-rich protein 1 (intestinal)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
GAS1 growth arrest-specific 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
JMJD6 jumonji domain containing 6
KAZN kazrin, periplakin interacting protein
KRT4 keratin 4, type II
KRT5 keratin 5, type II
LMO4 LIM domain only 4
LOC100505650 uncharacterized LOC100505650
MAMLD1 mastermind-like domain containing 1
MAT2A methionine adenosyltransferase II, alpha
NOP16 NOP16 nucleolar protein
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDGFA platelet-derived growth factor alpha polypeptide
PI3 peptidase inhibitor 3, skin-derived
PODXL podocalyxin-like
PRPF4 pre-mRNA processing factor 4
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TACSTD2 tumor-associated calcium signal transducer 2
TFRC transferrin receptor
TPM1 tropomyosin 1 (alpha)
TRAPPC3 trafficking protein particle complex 3
WFDC1 WAP four-disulfide core domain 1