BRD-K62810658_PD 98059_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K62810658_PD 98059_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BAD BCL2-associated agonist of cell death
CAST calpastatin
EFNA1 ephrin-A1
FCGBP Fc fragment of IgG binding protein
MTUS1 microtubule associated tumor suppressor 1
NUPR1 nuclear protein, transcriptional regulator, 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SESN1 sestrin 1

decreased expression

Symbol Name
ADM adrenomedullin
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA1 annexin A1
C2CD2 C2 calcium-dependent domain containing 2
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
FABP4 fatty acid binding protein 4, adipocyte
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
IER3 immediate early response 3
INPP1 inositol polyphosphate-1-phosphatase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NGRN neugrin, neurite outgrowth associated
NR4A2 nuclear receptor subfamily 4, group A, member 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLIN2 perilipin 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SMAD3 SMAD family member 3
SPRY2 sprouty homolog 2 (Drosophila)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase