BRD-K62810658_PD 98059_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K62810658_PD 98059_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADM adrenomedullin
ASS1 argininosuccinate synthase 1
BLNK B-cell linker
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFB complement factor B
COL3A1 collagen, type III, alpha 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DNTT DNA nucleotidylexotransferase
FGA fibrinogen alpha chain
FGG fibrinogen gamma chain
FOXO3 forkhead box O3
FSTL1 follistatin-like 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GC group-specific component (vitamin D binding protein)
GPM6B glycoprotein M6B
HILPDA hypoxia inducible lipid droplet-associated
IFI27 interferon, alpha-inducible protein 27
KRT4 keratin 4, type II
MME membrane metallo-endopeptidase
MT1F metallothionein 1F
OLFM4 olfactomedin 4
PBLD phenazine biosynthesis-like protein domain containing
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PLCB4 phospholipase C, beta 4
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRUNE2 prune homolog 2 (Drosophila)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PXDN peroxidasin
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
S100A8 S100 calcium binding protein A8
SELENBP1 selenium binding protein 1
SESN1 sestrin 1
SOD2 superoxide dismutase 2, mitochondrial
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX thymocyte selection-associated high mobility group box
VEGFA vascular endothelial growth factor A
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ANXA1 annexin A1
AXL AXL receptor tyrosine kinase
CRIP1 cysteine-rich protein 1 (intestinal)
CRIP2 cysteine-rich protein 2
CST3 cystatin C
DENND5A DENN/MADD domain containing 5A
DUSP4 dual specificity phosphatase 4
EGR3 early growth response 3
EXOSC4 exosome component 4
FAM129A family with sequence similarity 129, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
HOMER1 homer scaffolding protein 1
ICAM2 intercellular adhesion molecule 2
INPP1 inositol polyphosphate-1-phosphatase
KCTD12 potassium channel tetramerization domain containing 12
LAMP5 lysosomal-associated membrane protein family, member 5
LEF1 lymphoid enhancer-binding factor 1
LSR lipolysis stimulated lipoprotein receptor
MCL1 myeloid cell leukemia 1
MRPS30 mitochondrial ribosomal protein S30
NR4A2 nuclear receptor subfamily 4, group A, member 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLEC plectin
RGS2 regulator of G-protein signaling 2
SELL selectin L
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SRGN serglycin
STEAP1 six transmembrane epithelial antigen of the prostate 1
TSPYL4 TSPY-like 4