BRD-K62810658_PD 98059_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

21 genes differentially expressed following the BRD-K62810658_PD 98059_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
HSPA2 heat shock 70kDa protein 2
SOX2 SRY (sex determining region Y)-box 2

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
CD24 CD24 molecule
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
FZD7 frizzled class receptor 7
HES1 hes family bHLH transcription factor 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KRT7 keratin 7, type II
LEF1 lymphoid enhancer-binding factor 1
NPY neuropeptide Y
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPARG peroxisome proliferator-activated receptor gamma
RNF167 ring finger protein 167
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
STX1A syntaxin 1A (brain)
THBS1 thrombospondin 1
TM4SF1 transmembrane 4 L six family member 1
TMEM2 transmembrane protein 2
XIST X inactive specific transcript (non-protein coding)