BRD-K61220632_LEOIDIN DIMETHYL ETHER_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

210 genes differentially expressed following the BRD-K61220632_LEOIDIN DIMETHYL ETHER_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACPP acid phosphatase, prostate
ADAM10 ADAM metallopeptidase domain 10
ADGRF5 adhesion G protein-coupled receptor F5
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
AQP3 aquaporin 3 (Gill blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMCX1 armadillo repeat containing, X-linked 1
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CASP10 caspase 10, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
COL4A5 collagen, type IV, alpha 5
CSTA cystatin A (stefin A)
CXCL11 chemokine (C-X-C motif) ligand 11
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
DEGS1 delta(4)-desaturase, sphingolipid 1
DENND1B DENN/MADD domain containing 1B
DHRS3 dehydrogenase/reductase (SDR family) member 3
DPP4 dipeptidyl-peptidase 4
FAM129A family with sequence similarity 129, member A
FAM13A family with sequence similarity 13, member A
FAM69A family with sequence similarity 69, member A
FGL2 fibrinogen-like 2
FHOD3 formin homology 2 domain containing 3
FILIP1L filamin A interacting protein 1-like
FLT1 fms-related tyrosine kinase 1
FZD1 frizzled class receptor 1
FZD6 frizzled class receptor 6
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GPRASP1 G protein-coupled receptor associated sorting protein 1
H2AFV H2A histone family, member V
HHEX hematopoietically expressed homeobox
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IFI16 interferon, gamma-inducible protein 16
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA6 integrin, alpha 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
JUP junction plakoglobin
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KDR kinase insert domain receptor
KIAA1033 KIAA1033
KRT13 keratin 13, type I
KRT15 keratin 15, type I
LAMA4 laminin, alpha 4
LOC100505650 uncharacterized LOC100505650
LPAR6 lysophosphatidic acid receptor 6
LRP2 low density lipoprotein receptor-related protein 2
LYN LYN proto-oncogene, Src family tyrosine kinase
MAOA monoamine oxidase A
MEF2C myocyte enhancer factor 2C
MME membrane metallo-endopeptidase
MNDA myeloid cell nuclear differentiation antigen
MSMB microseminoprotein, beta-
NCAM1 neural cell adhesion molecule 1
NEB nebulin
NEFH neurofilament, heavy polypeptide
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOX4 NADPH oxidase 4
NRP1 neuropilin 1
NT5E 5'-nucleotidase, ecto (CD73)
OLFML2A olfactomedin-like 2A
PCP4 Purkinje cell protein 4
PECAM1 platelet/endothelial cell adhesion molecule 1
PERP PERP, TP53 apoptosis effector
PIEZO1 piezo-type mechanosensitive ion channel component 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCL1 phospholipase C-like 1
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POU2AF1 POU class 2 associating factor 1
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRAME preferentially expressed antigen in melanoma
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PTPRK protein tyrosine phosphatase, receptor type, K
PXN paxillin
PYCARD PYD and CARD domain containing
QPCT glutaminyl-peptide cyclotransferase
RAB27A RAB27A, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RNH1 ribonuclease/angiogenin inhibitor 1
RTN1 reticulon 1
SCD5 stearoyl-CoA desaturase 5
SERINC5 serine incorporator 5
SH3BGRL SH3 domain binding glutamate-rich protein like
SHB Src homology 2 domain containing adaptor protein B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SOCS2 suppressor of cytokine signaling 2
STC1 stanniocalcin 1
SULF1 sulfatase 1
SVIL supervillin
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TGFA transforming growth factor, alpha
TGM2 transglutaminase 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRD T cell receptor delta locus
TSPAN7 tetraspanin 7
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
YBX3 Y box binding protein 3
ZFP36 ZFP36 ring finger protein
ZFPM2 zinc finger protein, FOG family member 2
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ALCAM activated leukocyte cell adhesion molecule
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BST2 bone marrow stromal cell antigen 2
CCND1 cyclin D1
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
COMP cartilage oligomeric matrix protein
CST3 cystatin C
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL3 chemokine (C-X-C motif) ligand 3
CYFIP2 cytoplasmic FMR1 interacting protein 2
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F3 coagulation factor III (thromboplastin, tissue factor)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBXL12 F-box and leucine-rich repeat protein 12
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FST follistatin
FSTL1 follistatin-like 1
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GCH1 GTP cyclohydrolase 1
GMDS GDP-mannose 4,6-dehydratase
GOLGA7 golgin A7
GPX2 glutathione peroxidase 2
GSTT1 glutathione S-transferase theta 1
HACD2 3-hydroxyacyl-CoA dehydratase 2
JARID2 jumonji, AT rich interactive domain 2
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LTBP1 latent transforming growth factor beta binding protein 1
LYPLA1 lysophospholipase I
LYRM1 LYR motif containing 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
METRN meteorin, glial cell differentiation regulator
MGLL monoglyceride lipase
MRFAP1L1 Morf4 family associated protein 1-like 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1X metallothionein 1X
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
PCDH9 protocadherin 9
PCOLCE procollagen C-endopeptidase enhancer
PDLIM1 PDZ and LIM domain 1
PFKL phosphofructokinase, liver
PON2 paraoxonase 2
PPA1 pyrophosphatase (inorganic) 1
PPIF peptidylprolyl isomerase F
PRDX2 peroxiredoxin 2
PRKCZ protein kinase C, zeta
PROSC proline synthetase co-transcribed homolog (bacterial)
PRSS3 protease, serine, 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
QDPR quinoid dihydropteridine reductase
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RPS27L ribosomal protein S27-like
SCYL3 SCY1-like 3 (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SET SET nuclear proto-oncogene
SFN stratifin
SKP1 S-phase kinase-associated protein 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TMEM14A transmembrane protein 14A
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPBG trophoblast glycoprotein
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TSKU tsukushi, small leucine rich proteoglycan
TSPAN13 tetraspanin 13
TSPAN3 tetraspanin 3
TSPAN8 tetraspanin 8
TWIST1 twist family bHLH transcription factor 1
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1