BRD-K61220632_LEOIDIN DIMETHYL ETHER_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K61220632_LEOIDIN DIMETHYL ETHER_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
BID BH3 interacting domain death agonist
CA2 carbonic anhydrase II
CHN1 chimerin 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CSTA cystatin A (stefin A)
ELANE elastase, neutrophil expressed
FAM49A family with sequence similarity 49, member A
FOLR1 folate receptor 1 (adult)
FRY furry homolog (Drosophila)
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HSPA4 heat shock 70kDa protein 4
IL1RN interleukin 1 receptor antagonist
MMP9 matrix metallopeptidase 9
PTGDS prostaglandin D2 synthase 21kDa (brain)
S100A8 S100 calcium binding protein A8
SCGB2A1 secretoglobin, family 2A, member 1
SDC2 syndecan 2
TPD52L1 tumor protein D52-like 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
CETN3 centrin, EF-hand protein, 3
CGA glycoprotein hormones, alpha polypeptide
CLGN calmegin
G0S2 G0/G1 switch 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
LIPA lipase A, lysosomal acid, cholesterol esterase
NNMT nicotinamide N-methyltransferase
RBPMS RNA binding protein with multiple splicing
RGS2 regulator of G-protein signaling 2
RPA3 replication protein A3, 14kDa
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TFF1 trefoil factor 1
THBS4 thrombospondin 4
TXNDC9 thioredoxin domain containing 9