BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANO10 anoctamin 10
ATP9A ATPase, class II, type 9A
BLVRB biliverdin reductase B
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CBR1 carbonyl reductase 1
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CRABP2 cellular retinoic acid binding protein 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DSP desmoplakin
EPS8 epidermal growth factor receptor pathway substrate 8
FABP4 fatty acid binding protein 4, adipocyte
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JCHAIN joining chain of multimeric IgA and IgM
LOX lysyl oxidase
MAP1B microtubule-associated protein 1B
MARCKS myristoylated alanine-rich protein kinase C substrate
MDFIC MyoD family inhibitor domain containing
MTMR11 myotubularin related protein 11
NQO1 NAD(P)H dehydrogenase, quinone 1
PBX1 pre-B-cell leukemia homeobox 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SIRT3 sirtuin 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SULF1 sulfatase 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCAM1 vascular cell adhesion molecule 1
VCAN versican

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FXYD3 FXYD domain containing ion transport regulator 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
KIF5C kinesin family member 5C
LAMP5 lysosomal-associated membrane protein family, member 5
MAGEA3 melanoma antigen family A3
QDPR quinoid dihydropteridine reductase
TSPAN8 tetraspanin 8