BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_SNGM_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

118 genes differentially expressed following the BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_SNGM_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ARID5B AT rich interactive domain 5B (MRF1-like)
ASNS asparagine synthetase (glutamine-hydrolyzing)
BAG3 BCL2-associated athanogene 3
C10ORF10 chromosome 10 open reading frame 10
C1S complement component 1, s subcomponent
C3 complement component 3
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD163 CD163 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLDND1 claudin domain containing 1
CLEC2B C-type lectin domain family 2, member B
CNN3 calponin 3, acidic
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COLEC12 collectin sub-family member 12
CP ceruloplasmin (ferroxidase)
CRABP2 cellular retinoic acid binding protein 2
DCN decorin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF1 eukaryotic translation initiation factor 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
GJA1 gap junction protein, alpha 1, 43kDa
GLUL glutamate-ammonia ligase
HMOX1 heme oxygenase 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXD1 homeobox D1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IFRD1 interferon-related developmental regulator 1
IGFBP5 insulin-like growth factor binding protein 5
IGLL1 immunoglobulin lambda-like polypeptide 1
IPO13 importin 13
KIAA0753 KIAA0753
KRT19 keratin 19, type I
KRT6A keratin 6A, type II
LGALS8 lectin, galactoside-binding, soluble, 8
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LOX lysyl oxidase
MBNL2 muscleblind-like splicing regulator 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MYBPC1 myosin binding protein C, slow type
NQO1 NAD(P)H dehydrogenase, quinone 1
NRCAM neuronal cell adhesion molecule
NRIP1 nuclear receptor interacting protein 1
PCOLCE procollagen C-endopeptidase enhancer
PEG10 paternally expressed 10
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POLR1D polymerase (RNA) I polypeptide D, 16kDa
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
RRM2 ribonucleotide reductase M2
SEPP1 selenoprotein P, plasma, 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFN stratifin
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SRPX2 sushi-repeat containing protein, X-linked 2
STC2 stanniocalcin 2
SULF1 sulfatase 1
TF transferrin
TKT transketolase
TPD52 tumor protein D52
TPD52L1 tumor protein D52-like 1
TSPAN7 tetraspanin 7
TXNRD1 thioredoxin reductase 1
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ANOS1 anosmin 1
APOLD1 apolipoprotein L domain containing 1
AQP3 aquaporin 3 (Gill blood group)
BASP1 brain abundant, membrane attached signal protein 1
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BMP2 bone morphogenetic protein 2
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CTGF connective tissue growth factor
CTSC cathepsin C
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DACH1 dachshund family transcription factor 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DEGS1 delta(4)-desaturase, sphingolipid 1
DUSP3 dual specificity phosphatase 3
EIF5A eukaryotic translation initiation factor 5A
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FGF13 fibroblast growth factor 13
FZD1 frizzled class receptor 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
KRT7 keratin 7, type II
MGLL monoglyceride lipase
NELL2 NEL-like 2 (chicken)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIB nuclear factor I/B
PLK2 polo-like kinase 2
PNMA2 paraneoplastic Ma antigen 2
PROM1 prominin 1
RGS1 regulator of G-protein signaling 1
SFRP1 secreted frizzled-related protein 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
TOB2 transducer of ERBB2, 2
VAMP8 vesicle-associated membrane protein 8
VNN1 vanin 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble